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Therese Tripler

Institution
Yale University
ORCID
ORCID logo 0000-0001-9336-7271

Projects

Elucidating HIV-1 capsid interactions with host cofactors

Lead Institution
Yale University
Principal Investigator
Yong Xiong
Human immunodeficiency virus type 1 (HIV-1) infection is a global epidemic. Between the point of entry into the cell and integration of the HIV-1 genome into the host genome, the virus encounters…

HIV capsid retrograde trafficking complex

Lead Institution
Yale University
Principal Investigator
Yong Xiong
After attaching to the cell surface and membrane fusion, HIV releases the viral capsid into the target cells, which is transported to the cell nucleus. Evidence suggests that dynein-dynactin-BicD2…