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ShewFed


EMSL Project ID
12092

Abstract

Bacterial strains such as Shewanella oneidensis strain MR-1 are key organisms in the bioremediation of metals due to their ability to enzymatically reduce and precipitate a diverse range of heavy metals and radionuclides. Central to this reduction is the capacity of anaerobic respiration where the organism uses alternate electron acceptors in the respiratory process. We will use new technology based on the combination of global tryptic digestion, high-resolution liquid chromatography and tandem mass spectrometry and high field FTICR mass spectrometry to define determine the quantitative change in the protein expression patterns of the organism cultured under various levels of oxygen specifically aerobically, anaerobically and suboxically.

Project Details

Project type
Exploratory Research
Start Date
2005-03-08
End Date
2005-09-09
Status
Closed

Team

Principal Investigator

Mary Lipton
Institution
Environmental Molecular Sciences Laboratory