Accumulation of chromium in Shewanella oneidensis MR-1
EMSL Project ID
2283
Abstract
Objective : The objective of this project is to look at the final products obtained after biotransformation of chromate. We hypothesize that chromate is reduced to insoluble chromium hydroxide and that the accumulation of hydroxides within the cell results in inhibition of cell growth. Approach: To test this hypothesis, we plan to look at MR-1 grown in the presence of chromate using Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) to identify the possible locations of chromium accumulation inside MR-1. This will enable us to visualise the possible mechanisms that lead to chromate toxicity.
Project Details
Project type
Exploratory Research
Start Date
2001-07-16
End Date
2003-01-16
Status
Closed
Released Data Link
Team
Principal Investigator