NMR-Based Solution Structure of Escherichia coli Base Excision Repair Protein Formamidopyrimidine-DNA Glycosylase
EMSL Project ID
2330
Abstract
Cellular DNA is ceaselessly exposed to endogenous agents, such as the reactive free radicals produced during oxidative metabolism, and exogenous agents, such as ionizing radiation, that damage the DNA. Unrepaired, oxidative DNA lesions may have deleterious cellular consequences, including cell death, mutagenesis, carcinogenesis, and aging...
Project Details
Project type
Capability Research
Start Date
2001-10-01
End Date
2002-11-18
Status
Closed
Released Data Link
Team
Principal Investigator
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