Routine proton and carbon-13 NMR analysis of functionalized semiconductor quantum dots for biodetection studies
EMSL Project ID
3894
Abstract
The research included in this proposal involves the routine analysis of organic ligand-stabilized semiconductor nanoparticles that will serve as the signal transduction element in fluorescence-based biosensors. The semiconductor cores (typically CdSe or CdTe) of the nanoparticles are surrounded by an encapsulating layer of organic molecules which can be analyzed using standard solution-phase proton and carbon-13 NMR techniques. The purpose of this analysis is to determine the overall purity of the nanoparticle samples allowing for the comparison of organic ligands that are bound to the nanoparticle core to those that are free in solution. Usage of the instrument would be steady but light with a typical sample taking on the order of 5-15 minutes on a 300 MHz instrument.
Project Details
Project type
Capability Research
Start Date
2004-05-14
End Date
2004-09-29
Status
Closed
Released Data Link
Team
Principal Investigator