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Self-assembling highly stable biomimetic membranes from highly stable protein-like molecules


EMSL Project ID
49002

Abstract

The overall purpose of this research is to develop highly-stable sequence-specific molecules (called peptoids) to mimic proteins and peptides for functions. These peptoids will mimic the ability of proteins to exhibit secondary and tertiary structure, self-assemble into oligomeric complexes and extended ordered matrices. The structures of the peptoids, especially as it relates to their side chains, will lead to these self-organizing behaviors in solvent environments, resulting in distinctive and ultimately predictable behaviors. The peptoid assemblies developed will support both fundamental studies to understand pathways to assembly and self-organization, and also support the development of artificial membranes for energy applications such as water separations.

Project Details

Start Date
2015-06-04
End Date
2015-09-30
Status
Closed

Team

Principal Investigator

Chunlong Chen
Institution
Pacific Northwest National Laboratory