Projects

Nerve Agent Detection Using Enzyme-Coated Nanowires

Lead Institution

Pennsylvania State University

Principal Investigator

Seong Kim

Project type

Large-Scale EMSL Research

We propose a research program to prepare, characterize, and apply enzyme-coated nanowires to the detection of nerve agents. The substrate specificity of enzymatic reactions renders a great potential…

Toward preparation and operando characterization of nanostructured heterogeneous photocatalysts

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Glen Fryxell

Project type

Large-Scale EMSL Research

This proposal involves the use of EMSL facilities to characterize nanostructured TiO2 and its dopants. Standard structural tools will be used to characterize the TiO2 nanophases before and after…

Near Real-time Alkene Sensor for Atmospheric Aerosol Chemistry Monitoring

Lead Institution

MicroEnergy Technologies, Inc.

Principal Investigator

Reza Shekarriz

Project type

Large-Scale EMSL Research

The goal for the proposed project is to be able to take advantage of the current investments made at EMSL for the development of TDS to evaluate the potential for combining the TDS with the current…

Design of micro-cantilever actuators for measuring surface tension of sub microliter volumes applied towards monitoring interfacial processes

Lead Institution

Utah State University

Principal Investigator

David Britt

Project type

Large-Scale EMSL Research

It is well known that ambient moisture results in a capillary effect between AFM probes and surfaces when scanning in air. This phenomenon has been largely overlooked with respect to cantilever…

Microfabrication of Electrospray Emitter Arrays for Improved Sensitivity in Electrospray Ionization-Mass Spectrometry

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

Project type

Large-Scale EMSL Research

Liquid chromatography (LC), combined with mass spectrometry (MS), is an extremely powerful platform for protein analysis, allowing complex mixtures first separated by LC to be further resolved and…

Surface and Interface Studies of Photochemically Initiated Immobilization

Lead Institution

Portland State University

Principal Investigator

Mingdi Yan

Project type

Large-Scale EMSL Research

The ability to precisely control surface and interface properties is of paramount importance in applications ranging from catalysis, adhesion, sensing, to nanoscale devices. Critical to these…

The Effect of Surface Active Organic Molecules on the Water Uptake, Shape and Density of Hygroscopic Particles of Atmospheric Importance

Lead Institution

University of Colorado at Boulder

Principal Investigator

Gayfree Ellison

Project type

Large-Scale EMSL Research

This proposal is a continuation of research under EMSL User Proposal #16741. Field measurements of aerosol compositions consistently reveal that organics make up a significant fraction of the…

The Characterization of Diesel Exhaust Particle Matter and its Atmospheric Lifecycle: The Size, Shape and Composition of Soot Particles in the Atmosphere

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

George Muntean

Project type

Large-Scale EMSL Research

Elemental carbon or soot particles, the majority of which are emitted by diesel engines, significantly impact the Global Climate. Most atmospheric particles impact is to cool the planet by scattering…

The Cloud Nucleating Properties of Aerosols at a Continental Site: CHAPS Study

Lead Institution

Shenyang Pharmaceutical University

Principal Investigator

Jian Wang

Project type

Large-Scale EMSL Research

The primary goal of The Cumulus Humilis Aerosol Processing Study (CHAPS) is to characterize and contrast freshly emitted aerosols above, within and below fields of cumulus humilis (or fair-weather…

ClusterSculptor: An Expert Driven Visual Analytics Tool for the Classification of Single Particle Mass Spectra

Lead Institution

State University of New York at Stony Brook

Principal Investigator

Klaus Mueller

Project type

Large-Scale EMSL Research

This proposal is a continuation of research under EMSL User Proposal #3644. Single particle mass spectrometers and SPLAT in particular generate massive amounts of complex detailed data. Dr. Zelenyuk…

Experimental Investigation of Sr-90 Subsurface Contamination Sequestration in Hanford 100N Area Sediments by Surface Infiltration of an Apatite Solution

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James Szecsody

Project type

Large-Scale EMSL Research

Strontium-90 (Sr-90) discharge from past-practice liquid waste disposal sites in the Hanford 100N area have resulted in Sr-90 release to groundwater, Columbia River, and biota on the Columbia River…

Subsurface Reductive Elimination of Trichloroethylene using Zero-Valent Iron Emplaced by Polymer Solutions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Michael Truex

Project type

Large-Scale EMSL Research

Zero-valent iron (ZVI) has been used for in situ remediation of inorganic compounds and chlorinated solvents through engineered permeable reactive barriers and injectable ZVI particles. A key aspect…

Role of Surface and Interface on Transport Properties in Nanoscale Conducting Oxides

Lead Institution

University of South Carolina

Principal Investigator

Xiao-dong Zhou

Project type

Large-Scale EMSL Research

Size-dependent (&#8804;50 nm) chemical and physical properties of electronic materials have been attributed to primarily either intrinsic contributions, such as changes in the lattice energy and…

Material Homogeneity Studies on 3D Microfabricated Ceramic Structures Using Nanoparticle Building Blocks

Lead Institution

Oregon State University

Principal Investigator

Sundar Atre

Project type

Large-Scale EMSL Research

Nanoparticles are required for both geometric and performance attributes in numerous microscale applications. Curiously, numerous synthesis routes for nanoscale powders have been reported yet…

Characterizing the Composition, Morphology and Reactivity of Bacterial Nanowires using Advanced Scanning Probe Microscopy, MS-Based Proteomics and Scanning Electron Microscopy

Lead Institution

J. Craig Venter Institute

Principal Investigator

Yuri Gorby

Project type

Large-Scale EMSL Research

This project seeks to investigate the composition, morphology and reactivity of electrically conductive appendages known as bacterial nanowires. The research will capitalize on numerous analytical,…

Modeling Multiscale-Multiphase-Multicomponent Subsurface Reactive Flows using Advanced Computing

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Glenn Hammond

Project type

Large-Scale EMSL Research

During the course of the project we will apply PFLOTRAN to uranium migration at the Hanford 300 Area and to CO2 sequestration in subsurface geologic formations. In addition, we will test new…

Conformational Dynamics of Pin1 Regulation of APP processing and Abeta Production

Lead Institution

Cornell University

Principal Investigator

Linda Nicholson

Project type

Large-Scale EMSL Research

The proposed studies fall within the EMSL science theme of "Biological Interactions and Dynamics", specifically in the effort to understand how the "readout", or experimentally…

Mechanistic Studies of Protein Allostery at the Atomistic Scale

Lead Institution

University of California, Berkeley

Principal Investigator

Jhih-Wei Chu

Project type

Large-Scale EMSL Research

Allostery refers to the change of protein conformation in response to ligand binding, biochemical modifications, or interactions with other proteins. In this proposal, we plan to study protein…

STRUCTURAL STUDIES OF REGULATORS OF HISTONE PROTEIN SYNTHESIS

Lead Institution

University of North Carolina

Principal Investigator

Roopa Thapar

Project type

Large-Scale EMSL Research

STRUCTURAL STUDIES OF REGULATORS OF HISTONE PROTEIN SYNTHESIS. Roopa Thapar and William F. Marzluff In each cell cycle a eukaryotic cell must not only replicate its DNA, but must also…

The Aerosol Modeling Testbed

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jerome Fast

Project type

Large-Scale EMSL Research

An Aerosol Modeling Testbed will be developed that will simplify and greatly increase the efficiency of evaluating new aerosol treatments for regional and global climate models. The Aerosol Modeling…