Projects

Surface-Induced Dissociation of Complex Ions on an LTQ/Orbitrap Mass Spectrometer

Lead Institution

Purdue University

Principal Investigator

Julia Laskin

Project type

Large-Scale EMSL Research

Mass spectrometry is unique among instrumental analysis techniques in terms of its extraordinary sensitivity, molecular specificity and utility for addressing key questions in a broad range of…

Targeted identification of epigenetic determinants of T cell memory

Lead Institution

University of Tennessee

Principal Investigator

Heather Smallwood

Project type

Large-Scale EMSL Research

The ability to recognize previously encountered pathogens and rapidly eliminate them is critical to the immune system, as well as vaccine efficacy. A minute fraction of the millions of T cells…

Microscale Metabolic, Redox and Abiotic Reactions in Hanford 300 Area Subsurface Sediments

Lead Institution

Washington State University

Principal Investigator

Haluk Beyenal

Project type

Large-Scale EMSL Research

This proposal is the NMR component of a funded DOE/ERSP program project in which we proposed to use the Hanford 300 Area as a site for identifying microscale metabolic, abiotic and redox reactions in…

Rapidly Deployable Sensor Network

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Elizabeth Jurrus

Project type

Exploratory Research

Project Background Emerging networking technology provides unique opportunities for the rapid deployment and operation of clusters of sensor systems. The Rapidly Deployable Sensor Network (RDSN)…

PTR-MS Characterization of Carbon Nanotube Preconcentrators for Trace Chemical Signature Detection

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Feng Zheng

Project type

Exploratory Research

Nanoscience and technology has tremendous potential in the preparation of high surface area solids and chemically selective materials. Characterization of the uptake of chemicals for separations and…

Pore-Scale Investigation of the Impacts of Solution Chemistry on Mixing-Induced Mineral Precipitation in Silicon-Based Micromodels

Lead Institution

ExxonMobil Research and Engineering

Principal Investigator

Changyong Zhang

Project type

Exploratory Research

CO2 sequestration in geologic formations is increasingly being studied as a strategy for limiting CO2 emission to the atmosphere, but there are potentials for geochemical reactions in the reservoirs…

Study of Kinetics of Oxide Scale Formation in air on Nicrofer-6025HT for Clean Coal Energy Delivery and other High Temperature Applications using XPS

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jens Darsell

Project type

Exploratory Research

Oxygen separation membranes for clean coal energy delivery in advanced coal based power plants rely on use of solid state electronic and ionic conductors which operate at temperatures in the range…

Microscale Spectroscopic Analyses of Cellulose Degradation and
Uptake by a Microbial Community

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Nancy Hess

Project type

Exploratory Research

We seek to describe the acquisition and incorporation of cellulose-derived C into a complex microbial community that was been enriched from soil. In doing so at batch culture scales we will further…

Pacific Northwest National Laboratory's Technology Assistance Program

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Gary Spanner

Project type

Exploratory Research

The Energy Policy Act of 2005 mandates that the United States' national laboratories offer technology assistance to small businesses. The Technology Assistance Program (TAP) operated by the…

Design of plasmonic probe tips to control light on the nanoscale for imaging and spectroscopy with ultrahigh spatial and temporal resolution

Lead Institution

University of Colorado at Boulder

Principal Investigator

Bernd Raschke

Project type

Exploratory Research

The optical probing of matter with simultaneous nanometer spatial and femtosecond temporal resolution has remained a great challenge. Here, using focused ion beam milling we will tune the optical…

Elucidation of Structure-Activity Relationship in Nanoparticle Inhalation Toxicology

Lead Institution

Battelle Columbus

Principal Investigator

Amit Gupta

Project type

Exploratory Research

Multiwalled Carbon Nanotubes (MWCNT) are of great commercial interest. However, with increasing applications and production capacities of MWCNT, they are coming under intense scrutiny by the…

VEGETATION INFLUENCES ON LONG-TERM CARBON STABILIZATION IN SOILS, VIA PLANT ALLOCATION, TISSUE CHEMISTRY,
AND SOIL DEPTH EFFECTS

Lead Institution

Lawrence Berkeley National Laboratory

Principal Investigator

Margaret Torn

Project type

Exploratory Research

Soil organic matter is a major reservoir of carbon within the biosphere and has a fundamental impact on soil properties, and therefore on ecosystem functioning and sustainability. We are proposing to…

Impacts of Pore Scale Heterogeneity on Nanoparticle Motility and Transport: A Micromodel Study

Lead Institution

ExxonMobil Research and Engineering

Principal Investigator

Changyong Zhang

Project type

Exploratory Research

The increasing production, application and disposal of functionalized nanomaterials will inevitably lead to wide environmental impacts. Motility and transport of nanoparticles in the subsurface…

Pathogen Control for a Sustainable Reuse of Wastewater: Role of Surface Interactions on Transport of Cryptosporidium parvum oocysts in Subsurface

Lead Institution

University of Illinois at Urbana-Champaign

Principal Investigator

Thanh Nguyen

Project type

Exploratory Research

Transport of pathogens such as Cryptosporidium parvum oocysts in subsurface environment is of great concern for water resources protection or drinking water treatment. Groundwater source for drinking…

Monitoring the Global Conformation of SRP During Co-translational Protein Targeting

Lead Institution

California Institute of Technology

Principal Investigator

Vinh Lam

Project type

Exploratory Research

The signal recognition particle (SRP) is the major cellular machinery that mediates co-translational targeting of membrane and secretory proteins to the eukaryotic endoplasmic reticulum (ER) membrane…

Structure-Function Relationships in Nanoscale Electrocatalysis

Lead Institution

University of Washington

Principal Investigator

Bo Zhang

Project type

Exploratory Research

The goal of this proposal is to investigate the relationship between electrocatalytic activity and geometric characteristics at single metal nanowires. A key aspect of the proposed research is that…

Nanoparticle Characterization for Systems Analysis of Biocompatibility

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Barbara Tarasevich

Project type

Exploratory Research

The goal of this research is to develop an understanding of how the physicochemical properties of nanomaterials influence their ability to interact with cells and stimulate biological responses. The…

Computational Study of Protein-Protein Interaction Dynamics at Single Molecule Level

Lead Institution

State University of New York at Stony Brook

Principal Investigator

Jin Wang

Project type

Exploratory Research

The dynamic process of binding occurs in a wide dynamic range, including millisecond to second timescale range. To be able to connect and compare computational simulation results with the results…

COMBINED EPR, NMR, MAGNETIC SUSCEPTIBILITY AND COMPUTATIONAL DETERMINATION OF RARE EARTH HYPERFINE EFFECTS IN CERAMICS.

Lead Institution

University of Cambridge

Principal Investigator

Ian Farnan

Project type

Exploratory Research

The first successful high-resolution solid-state NMR experiments on plutonium containing ceramics were carried out at EMSL. As these breakthrough experiments are exploited in the radiological NMR…

Xenoestrogen effect on trout histones

Lead Institution

University of Idaho

Principal Investigator

James Nagler

Project type

Exploratory Research

We are using a fish model, the rainbow trout, as a human surrogate to investigate the reproductive consequences of xenoestrogen exposure on male reproduction. Our previous studies have documented…