Projects

As a scientific user facility, the Environmental Molecular Sciences Laboratory (EMSL) provides expertise, instrumentation, and resources to 250 projects each year.

EMSL projects displayed on the EMSL web site project page reflect project abstracts and information migrated to this page before April 30, 2024. To review current and past EMSL user projects, visit EMSL Science Central.™

The Cloud Nucleating Properties of Aerosols at a Continental Site: CHAPS Study

Lead Institution

Shenyang Pharmaceutical University

Principal Investigator

Jian Wang

Project type

Large-Scale EMSL Research

The primary goal of The Cumulus Humilis Aerosol Processing Study (CHAPS) is to characterize and contrast freshly emitted aerosols above, within and below fields of cumulus humilis (or fair-weather…

ClusterSculptor: An Expert Driven Visual Analytics Tool for the Classification of Single Particle Mass Spectra

Lead Institution

State University of New York at Stony Brook

Principal Investigator

Klaus Mueller

Project type

Large-Scale EMSL Research

This proposal is a continuation of research under EMSL User Proposal #3644. Single particle mass spectrometers and SPLAT in particular generate massive amounts of complex detailed data. Dr. Zelenyuk…

Experimental Investigation of Sr-90 Subsurface Contamination Sequestration in Hanford 100N Area Sediments by Surface Infiltration of an Apatite Solution

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James Szecsody

Project type

Large-Scale EMSL Research

Strontium-90 (Sr-90) discharge from past-practice liquid waste disposal sites in the Hanford 100N area have resulted in Sr-90 release to groundwater, Columbia River, and biota on the Columbia River…

Subsurface Reductive Elimination of Trichloroethylene using Zero-Valent Iron Emplaced by Polymer Solutions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Michael Truex

Project type

Large-Scale EMSL Research

Zero-valent iron (ZVI) has been used for in situ remediation of inorganic compounds and chlorinated solvents through engineered permeable reactive barriers and injectable ZVI particles. A key aspect…

Role of Surface and Interface on Transport Properties in Nanoscale Conducting Oxides

Lead Institution

University of South Carolina

Principal Investigator

Xiao-dong Zhou

Project type

Large-Scale EMSL Research

Size-dependent (&#8804;50 nm) chemical and physical properties of electronic materials have been attributed to primarily either intrinsic contributions, such as changes in the lattice energy and…

Material Homogeneity Studies on 3D Microfabricated Ceramic Structures Using Nanoparticle Building Blocks

Lead Institution

Oregon State University

Principal Investigator

Sundar Atre

Project type

Large-Scale EMSL Research

Nanoparticles are required for both geometric and performance attributes in numerous microscale applications. Curiously, numerous synthesis routes for nanoscale powders have been reported yet…

Characterizing the Composition, Morphology and Reactivity of Bacterial Nanowires using Advanced Scanning Probe Microscopy, MS-Based Proteomics and Scanning Electron Microscopy

Lead Institution

J. Craig Venter Institute

Principal Investigator

Yuri Gorby

Project type

Large-Scale EMSL Research

This project seeks to investigate the composition, morphology and reactivity of electrically conductive appendages known as bacterial nanowires. The research will capitalize on numerous analytical,…

Modeling Multiscale-Multiphase-Multicomponent Subsurface Reactive Flows using Advanced Computing

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Glenn Hammond

Project type

Large-Scale EMSL Research

During the course of the project we will apply PFLOTRAN to uranium migration at the Hanford 300 Area and to CO2 sequestration in subsurface geologic formations. In addition, we will test new…

Conformational Dynamics of Pin1 Regulation of APP processing and Abeta Production

Lead Institution

Cornell University

Principal Investigator

Linda Nicholson

Project type

Large-Scale EMSL Research

The proposed studies fall within the EMSL science theme of "Biological Interactions and Dynamics", specifically in the effort to understand how the "readout", or experimentally…

Mechanistic Studies of Protein Allostery at the Atomistic Scale

Lead Institution

University of California, Berkeley

Principal Investigator

Jhih-Wei Chu

Project type

Large-Scale EMSL Research

Allostery refers to the change of protein conformation in response to ligand binding, biochemical modifications, or interactions with other proteins. In this proposal, we plan to study protein…

STRUCTURAL STUDIES OF REGULATORS OF HISTONE PROTEIN SYNTHESIS

Lead Institution

University of North Carolina

Principal Investigator

Roopa Thapar

Project type

Large-Scale EMSL Research

STRUCTURAL STUDIES OF REGULATORS OF HISTONE PROTEIN SYNTHESIS. Roopa Thapar and William F. Marzluff In each cell cycle a eukaryotic cell must not only replicate its DNA, but must also…

The Aerosol Modeling Testbed

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jerome Fast

Project type

Large-Scale EMSL Research

An Aerosol Modeling Testbed will be developed that will simplify and greatly increase the efficiency of evaluating new aerosol treatments for regional and global climate models. The Aerosol Modeling…

Coupled Hydrological and Geochemical Studies on Uranium Plumes at Hanford Site: Reactions, Spatial Distributions, Speciation, and Future Mobility

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Zheming Wang

Project type

Large-Scale EMSL Research

Massive quantities (exceeding 85 tons) of U currently reside in the Hanford vadose zone, and will threaten groundwater and the accessible environment for generations to come. Present insufficient…

Interfacial Phenomena in Cu Plating

Lead Institution

eMAT Technology LLC

Principal Investigator

Valery Dubin

Project type

Large-Scale EMSL Research

Electroplated Cu on a physical vapor deposited (PVD) Cu seed layer with a PVD Ta-based barrier is now an integrated process for the production of advanced interconnects for integrated circuits (IC),…

Mechanisms of Ubiquitin Transfer and Regulation

Lead Institution

University of Washington

Principal Investigator

Rachel Klevit

Project type

Large-Scale EMSL Research

Protein ubiquitination is a powerful regulatory process that influences nearly every aspect of eukaryotic cell biology. Pathways ranging from cell-cycle progression and differentiation to DNA repair…

Exploring the Proteome of E. coli Following Adaptation to Environmental and Genetic Perturbation

Lead Institution

University of California, San Diego

Principal Investigator

Bernhard Palsson

Project type

Large-Scale EMSL Research

Microorganisms rapidly adapt to changes in the environment which ensures their survival under suboptimal conditions. It is well known that microorganisms display genomic plasticity that enables…

Experimental and Theoretical Investigations on the
Chemistry and Dynamics of Ammonia Borane Dehydrogenation

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Thomas Autrey

Project type

Large-Scale EMSL Research

Increasing demands for clean energy sources that do not add CO2 and other pollutants to the environment have resulted in increased worldwide interest in the possibilities of a "hydrogen economy…

Determination of the CCR5 and CXCR4 Antagonist and Agonist Binding Site.

Lead Institution

Montana State University

Principal Investigator

Edward Dratz

Project type

Large-Scale EMSL Research

This proposal focuses on determining the locations of the agonist and antagonist binding pockets for the 7-transmembrane spanning G-Protein coupled receptors (GPCR) CCR5 and CXCR4. G-protein coupled…

Proteomic-based mechanistic analysis of components involved in the immunoprotective pathways regulated by low-dose radiation and the medicinal mushroom Trametes versicolor

Lead Institution

Bastyr University

Principal Investigator

Cynthia Wenner

Project type

Large-Scale EMSL Research

The goal of this proposal is to identify molecular mechanisms that underlie radio-adaptive immune responses. We propose to use quantitative mass spectrometry to investigate the effects of…

Doping inorganic wide-bandgap semiconductors for future energy devices

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Weilin Jiang

Project type

Large-Scale EMSL Research

Solid-state lighting (SSL) has a significantly higher efficiency of converting electricity to visible light compared to the incandescent (5%) or fluorescent (20%) lighting due to elimination of…

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