Alla Kostyukova

Washington State University

0000-0002-6724-2069

Projects

Structure of the binding interface between tropomodulin and tropomyosin

Lead Institution

Washington State University

Principal Investigator

Alla Kostyukova

In striated muscles, actin thin filament architecture is critical for efficient contractile activity, and alterations in the thin filament length are linked to severe and often lethal muscle diseases…

Structure of the binding interface between leiomodin and tropomyosin.

Lead Institution

Washington State University

Principal Investigator

Alla Kostyukova

Project type

Limited Scope

Cardiac muscle cells contain two types of protein filaments composed of either actin or myosin. The filaments slide past one another and produce force in the heart muscle. For healthy heart…