Austin Gluth

Integrative Multi-PTM Profiling by an Automated Shotgun Proteomics Coupled with Top-down Proteomics

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Tong Zhang

Project type

Contracted Time

To use PTM data to understand cell signaling and profile molecular phenotypes, PNNL has made substantial strides in advancing phosphoproteome and thiol redox proteome profiling. However, the current…

Integrative Multi-PTM Profiling by an Automated Shotgun Proteomics Coupled with Top-down Proteomics

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Tong Zhang

To use PTM data to understand cell signaling and profile molecular phenotypes, PNNL has made substantial strides in advancing phosphoproteome and thiol redox proteome profiling. However, the current…

Pathways and Critical Regulators of Early Beta-cell Dysfunction in Type 1 Diabetes

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Weijun Qian

Type 1 diabetes (T1D) is a complex autoimmune disease. Recent clinical studies show that pancreatic beta-cell dysfunction (e.g., a decline of first phase insulin release) occurs several years before…

Pathways and Critical Regulators of Early Beta-cell Dysfunction in Type 1 Diabetes

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Weijun Qian

Type 1 diabetes (T1D) is a complex autoimmune disease. Recent clinical studies show that pancreatic beta-cell dysfunction (e.g., a decline of first phase insulin release) occurs several years before…

Characterizing Key Factors That Influence Recalcitrance of Lignocellulosic Biomass Deconstruction via in-situ liquid IR SNOM Approach

Lead Institution

Washington State University Tri-Cities

Principal Investigator

Bin Yang

Project type

Exploratory Research

Call Topic: This proposal is in response to Functional and Systems Biology on EMSL’s suite of surface science capabilities are ideal for chemical imaging organic matter mineral interactions…

EMSL Science Overview

Austin Gluth

Projects

Integrative Multi-PTM Profiling by an Automated Shotgun Proteomics Coupled with Top-down Proteomics

Integrative Multi-PTM Profiling by an Automated Shotgun Proteomics Coupled with Top-down Proteomics

Pathways and Critical Regulators of Early Beta-cell Dysfunction in Type 1 Diabetes

Pathways and Critical Regulators of Early Beta-cell Dysfunction in Type 1 Diabetes

Characterizing Key Factors That Influence Recalcitrance of Lignocellulosic Biomass Deconstruction via in-situ liquid IR SNOM Approach