Skip to main content

Brian Thrall

Institution
Pacific Northwest National Laboratory

Projects

Proteomic Analysis of the HMEC Mitogenic Response

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Brian Thrall
Project type
Exploratory Research
This EMSL User Proposal is for a collaborative effort with the PNNL Proteomic National Center for Research Resources. Recent studies from our and others’ laboratories have demonstrated that the…

Secretome Analysis of Environmental Nanoparticle Induced Biomarkers

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Jon Jacobs
A national goal for particulate matter (PM) research centers is to develop biological markers of specific mechanistic pathways that can be used to link findings from animal, human and epidemiological…

Molecular analysis of cancer by FTICR

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Brian Thrall
Project type
Exploratory Research
Proteomic analysis of wild-type versus cancerous tumor cells.

Collaborative Research Projects Supported by the NCRR P41 Resource Center

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
David Camp
Project type
Large-Scale EMSL Research
The Proteomics Resource Center for Integrative Biology at PNNL was established in 2003 and builds on the unique instrumentation and the infrastructure provided by PNNLs EMSL facility. The mission of…

Computer Simulations of Protein-Nanomaterial Interactions

Lead Institution
Universidade Federal de Pernambuco
Principal Investigator
Roberto Lins Neto
Project type
Capability Research
The development of nanotechnology has led to an increasing interest in interfacing biological molecules with nanomaterials. Proteins have been used to functionalize nanomaterials controlling their…

Nanoparticle Characterization for Systems Analysis of Biocompatibility

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Barbara Tarasevich
Project type
Exploratory Research
The goal of this research is to develop an understanding of how the physicochemical properties of nanomaterials influence their ability to interact with cells and stimulate biological responses. The…

Membrane Receptor-Directed Nanomaterial-Cell Interactions

Lead Institution
University of Montana
Principal Investigator
Andrij Holian
Project type
Large-Scale EMSL Research
The global market for nanotechnology is expected to grow to ~$3 trillion by 2015 and with the increased fabrication and usage of nanomaterials the potential for exposure of nanotechnology workers and…

A Variable Energy Electron Mibrobeam

Lead Institution
NASA Ames Research Center
Principal Investigator
Marianne Sowa
Project type
Exploratory Research
A variable energy electron microbeam has been developed and is being utilized for various biological studies.