Joshua Turse

Analysis of the Proteome and Transcriptome of In Vivo Brucella spp., Yersinia pestis, Francisella tularensis, Mycobacterium spp., Salmonella typhimurium Infected Ileum

Lead Institution

Texas A&M University

Principal Investigator

Leslie Adams

Project type

Large-Scale EMSL Research

The host responses to Brucella spp., Yersinia pestis, Francisella tularensis, Mycobacterium spp., Salmonella typhimurium and the pathogen responses to the host play major roles in the outcome of…

Application of High-Throughput Proteomics

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Mary Lipton

The understanding of how cells function at the systems level will greatly benefit from the development of new approaches capable of making global measurements of protein expression (proteome). The…

Coupling temporal variations in geochemistry to activities of microbial populations in the deep subseafloor biosphere

Lead Institution

Harvard University

Principal Investigator

Peter Girguis

Project type

Large-Scale EMSL Research

To date, studies of the oceanic subsurface biosphere have effectively demonstrated the existence of an active microbial community, and have begun to characterize community density and distribution…

Burkholderia Proteomoics

Lead Institution

University of Medicine and Dentistry, New Jersey Medical School

Principal Investigator

Steven Schutzer

Project type

Large-Scale EMSL Research

Burkholderia mallei, a biothreat agent, is the causative bacterial agent of glanders. Currently, there is no rapid discriminating diagnostic assay, no vaccine, and no reliable therapy. Gaps in our…

High-Throughput Proteomics: Applications and Development (PNNL Scope #40601 and #43488)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Gordon Anderson

This project involves the application and development of high-throughput proteomics and quantitative measurement capabilities within biological systems. More so, application measurements will be…

Identification of Dermacentor Andersoni Saliva Proteins that Modulate Mammalian Phagocyte Function

Lead Institution

Washington State University

Principal Investigator

Wendy Brown

Project type

Limited Scope

Dermacentor andersoni, known as the Rocky Mountain wood tick, is a species of tick found in the western United States. Ticks are obligate blood sucking parasites which transmit a wide range of…

EMSL Science Overview

Joshua Turse

Projects

Analysis of the Proteome and Transcriptome of In Vivo Brucella spp., Yersinia pestis, Francisella tularensis, Mycobacterium spp., Salmonella typhimurium Infected Ileum

Application of High-Throughput Proteomics

Coupling temporal variations in geochemistry to activities of microbial populations in the deep subseafloor biosphere

Burkholderia Proteomoics

High-Throughput Proteomics: Applications and Development (PNNL Scope #40601 and #43488)

Identification of Dermacentor Andersoni Saliva Proteins that Modulate Mammalian Phagocyte Function