Melanie Ohi

University of Michigan

0000-0003-1750-4793

Projects

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

James Evans

PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

Structural characterization of the Helicobacter pylori Cag T4SS using single particle cryo-EM

Lead Institution

University of Michigan

Principal Investigator

Melanie Ohi

Using cryo-EM we determined the structure of the 5.6 MDa H. pylori Cag T4SS at a resolution of ~3.6 Å. The Hp T4SS is structurally different from T4SS structures seen in other species and has an…