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Richard Zangar

Institution
Pacific Northwest National Laboratory

Projects

Zangar NAF R33

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Zangar
Breast cancer is responsible for ~43,000 deaths per year, a number which could be reduced dramatically by early detection of the disease. Currently, detection of breast cancer relies primarily on…

High-Throughput Evaluation of Breast Cancer Markers

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Zangar
The following abstract was adapted from the NIH/NCI proposal that has been funded by the Early Detecion Research Network at NCI. Breast cancer is one of the most prevalent cancer in the United…

Platelet secretome

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Zangar
This work is being done in collaboration with Dr. Richard Phipps at University of Rochester Medical Center. His interests are in the study of platelet activation and inflamatory markers,…

Breast Cancer Biomarkers in Nipple Aspirate Fluid

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Zangar
Project type
Exploratory Research
Breast cancer is responsible for ~43,000 deaths per year, a number which could be reduced dramatically by early detection of the disease. Currently, detection of breast cancer relies primarily on…

POSTTRANSLATIONAL MODIFICATIONS FOR EARLY DETECTION OF BREAST CANCER

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Zangar
Project type
Large-Scale EMSL Research
Breast cancer is the most common cancer in women and is the second leading cause of death due to cancer. The goal of this study is to use proteomics to identify post-translational modifications …

Determination of the C-terminus of p110 sEGFR

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Zangar
Project type
Exploratory Research
A 110 kDa, soluble fragment of the EGFR protein (p110 sEGFR) has been identified as a circulating marker of cancer (Maihle and coworkers, 1998, 1999). The p110 sEGFR is released into the serum as…

Global measurments of phosphopeptides in human mammary epithelial cells.

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Richard Zangar
Project type
Exploratory Research
There is a need to understand fundamental regulatory mechanisms that regulate cell growth and differentiation in breast cells. This information can lead to new routes of treating or preventing…