William Clemons

California Institute of Technology

0000-0002-0021-889x

Projects

Structural determination of the key membrane protein in peptidoglycan synthesis, MraY, in the presence of inhibitors

Lead Institution

California Institute of Technology

Principal Investigator

William Clemons

In the continuous race against bacterial infections, the development of new drugs becomes essential to find new ways to fight multidrug resistant bacteria. MraY catalyzes the first membrane step in…

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

James Evans

PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

Structural studies of the targeting factor Get3

Lead Institution

California Institute of Technology

Principal Investigator

William Clemons

Tail-anchored (TA) proteins, accounting for approximately 2% of the genome, are a class of proteins with various functions but all with a single transmembrane domain near their C-terminus. Due to the…