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Yong Xiong

Institution
Yale University

Projects

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
James Evans
PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

HIV capsid retrograde trafficking complex

Lead Institution
Yale University
Principal Investigator
Yong Xiong
After attaching to the cell surface and membrane fusion, HIV releases the viral capsid into the target cells, which is transported to the cell nucleus. Evidence suggests that dynein-dynactin-BicD2…

Elucidating HIV-1 capsid interactions with host cofactors

Lead Institution
Yale University
Principal Investigator
Yong Xiong
Human immunodeficiency virus type 1 (HIV-1) infection is a global epidemic. Between the point of entry into the cell and integration of the HIV-1 genome into the host genome, the virus encounters…