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Zhe Chen

Institution
University of Texas Southwestern Medical Center
ORCID
ORCID logo 0000-0002-1668-4051

Projects

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
James Evans
PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

Nuclear import of histone H2A-H2B and histone chaperone Nap1 by Kap114

Lead Institution
University of Texas Southwestern Medical Center
Principal Investigator
Yuh Chook
Core histones organize DNA in the nucleus. Histones are synthesized in the cytoplasm and are be transported by to the nucleus by Karyopherin nuclear transport receptors. In the cytoplasm, histones…

Nuclear export of phosphorylated proteins by Karyopherin MSN5

Lead Institution
University of Texas Southwestern Medical Center
Principal Investigator
Yuh Chook
MSN5 is the 142 kDa S. cerevisiae exportin, which exports many different protein cargoes from the nucleus to the cytoplasm in response to cellular environmental changes. Peptide signals in several…