Peptide biomarker Analysis
EMSL Project ID
18897
Abstract
This proposal is for use of ESI-MS (LTQ orbitrap)for analysis of native peptide markers. Sets of peptide masses from the LC-MS runs will be acquired and initially used as raw data for comparison. This is part of the environmental biomarkers initiative work on markers of response to infection and vaccination. The standard peptide analysis conditions used on that instrument would be utilized.
Project Details
Start Date
2006-04-21
End Date
2009-04-26
Status
Closed
Released Data Link
Team
Principal Investigator
Related Publications
Varnum SM, BJM Webb-Robertson, JG Pounds, RJ Moore, RD Smith, C Frevert, SJ Skerret, and DS Wunschel. 2012. "Proteomic analysis of bronchoalveolar lavage fluid proteins from mice infected with Francisella tularensis ssp novicida." Journal of Proteome Research 11(7):3690-3703.
Webb-Robertson BJM, LA McCue, N Beagley, JE McDermott, DS Wunschel, SM Varnum, JZ Hu, NG Isern, GW Buchko, K Mcateer, JG Pounds, SJ Skerret, D Liggitt, and CW Frevert. 2009. "A Bayesian Integration Model of High-Throughput Proteomics and Metabolomics Data for Improved Early Detection of Microbial Infections." In Pacific Symposium on Biocomputing, vol. 14, pp. 451-463. World Scientific Publishing Co., Singapore, Singapore.