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Structural Genomics of Eukaryotic Model Organisms


EMSL Project ID
2170

Abstract

The primary genome targets for this methodology development are eukaryotic model organisms which are subjects of extensive functional genomics research, including S. cerevisiae, C. elegans, and D. melanogaster, as well as homologues from the human genome. Structure and sequence data is being combined using bioinformatics methods to refine our understanding of the evolutionary relationships between proteins, and to develop specific hyptheses regarding potential biochemical functions of these proteins, and to develop specific hypotheses regarding potential biochemical functions of these proteins.

Project Details

Project type
Capability Research
Start Date
2001-08-01
End Date
2001-09-11
Status
Closed

Team

Principal Investigator

Gaetano Montelione
Institution
Rutgers University

Related Publications

Yin C, JM Aramini, LC Ma, JR Cort, GVT Swapna, RM Krug, and G Montelione. 2011. "Backbone and Ile-?1, Leu, Val Methyl 1H, 13C and 15N NMR chemical shift assignments for human interferon-stimulated gene 15 protein." Biomolecular NMR Assignments 5(2):215-219. doi:10.1007/s12104-011-9303-8