Demonstrate a systematic application of a magnetic tweezers: holding a protein molecule in solution
EMSL Project ID
23690a
Abstract
Over the last three years, we have collaborated with Ms. Beveley Taylor in IDL/EMSL to develop a magnetic tweezers technique that is capable of holding a magnetic-beed tethered single molecule in solution. This device allows one to study protein conformational dynamics and functions in its native state under physiological relevant conditions. We propose to conduct a systematic examination of the device operation and application at BGSU single-molecule spectroscopy lab.
Project Details
Project type
Exploratory Research
Start Date
2008-03-20
End Date
2009-03-22
Status
Closed
Released Data Link
Team
Principal Investigator