Structural genomics of eukaryotic model organisms
EMSL Project ID
3992
Abstract
ABSTRACT The Northeast Structural Genomics Consortium is a NIH-funded pilot
project aimed at evaluating the feasibility, costs, economies of scale, and
value of structural proteomics. The primary goal of our pilot project is to
develop integrated technologies for high-throughput (htp) protein production
and 3D structure determination. Our NESG Consortium has the particular focus
of evaluating the role of protein NMR spectroscopy in future Structural
Proteomics Centers to be funded by NIH. Our targets include members of large
protein families for which no 3D structural information is available. We
prioritize protein families with representatives in human and higher
eukaryotic genomes because of the important role of these proteins in human
health and model organism biology. NMR data collection at Pacific Northwest
National Laboratories,
in collaboration with Dr. Micheal Kennedy and Dr. John Cort, and the
structures resulting from these data are critical to the
efficacy of this project.
Project Details
Project type
Capability Research
Start Date
2003-10-01
End Date
2004-09-30
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members
Related Publications
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PNNL Technical Report PNNL-20368
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