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Forensic Proteomics of Viruses


EMSL Project ID
43096

Abstract

The previous proteomic analysis of vaccinia virus (VV) and Monkeypox viruses has indicated that a significant amount of host cellular protein associates itself with virus preparations. Some of these proteins are likely integral irus components while others are simply difficult to remove. The combination of viral and host proteins provide a potential forensic production signature. This proposal will extend that work focusing on different methods of virus production and purification.

Project Details

Start Date
2011-01-13
End Date
2013-11-20
Status
Closed

Team

Principal Investigator

David Wunschel
Institution
Pacific Northwest National Laboratory

Team Members

Heather Engelmann
Institution
Pacific Northwest National Laboratory

Brian Clowers
Institution
Washington State University