Cryo-EM studies of trapped nuclear 60S ribosome biogenesis intermediates
EMSL Project ID
51585
Abstract
We have genetically engineered yeast strain to trap distinct intermediates in the large ribosomal subunit maturation pathway. Single particle reconstructions of these particles reveal the function of large macromolecular complexes in regulating the rearrangement of rRNA elements within nuclear 60S particles.
Project Details
Start Date
2020-07-15
End Date
2021-03-17
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members