Computational study of protein-protein interaction dynamics
EMSL Project ID
5690
Abstract
Protein-protein interactions are extremely important and complex in livingcells. Studying the dynamical processes of protein-protein interactions is
crucial for uncovering the fundamental mechanisms and dynamics governing
cellular functions, such as the cell signaling processes. It would also
help the understanding of the complex biological network involving
protein-protein interactions in bacterial cells. In this project, we plan
to carry out a systematic simulation study on the dynamics of
protein-protein interactions using our new parallel computation facility.
These new capability and fundamental understanding will significantly
enhance our single-molecule spectroscopy studies on protein-protein
interaction dynamics in Genome-To-Life (DOE) and System Biology Initiative
(LDRD; PNNL) projects.
Project Details
Project type
Capability Research
Start Date
2004-01-30
End Date
2006-02-06
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members