Ion Channel Protein Dynamics in Lipid Bilayer
EMSL Project ID
6511
Abstract
Voltage controlled protein ion channel in lipid bilayer will be studied by using patch-clamp confocal fluorescence imaging microscopy and single molecule spectroscopy.
Project Details
Project type
Exploratory Research
Start Date
2004-11-01
End Date
2006-11-07
Status
Closed
Released Data Link
Team
Principal Investigator
Related Publications
Biju VP, D Pan, YA Gorby, JK Fredrickson, JS McLean, D Saffarini, and HP Lu. 2007. "Combined Spectroscopic and Topographic Characterization of Nanoscale Domains and Their Distributions of a Redox Protein on Bacterial Cell Surfaces." Langmuir 23(3):1333-1338. doi:10.1021/la061343z
Harms G, G Orr, and HP Lu. 2004. "Probing Ion Channel Conformational Dynamics using Simultaneous Single-Molecule Ultrafast Spectroscopy and Patch-Clamp Electric Recording." Applied Physics Letters 84(10):1792-1794.
Harms GS, G Orr, M Montal, BD Thrall, SD Colson, and HP Lu. "Probing Conformational Changes of Gramicidin Ion Channels by Single-Molecule Patch-Clamp Fluorescence Microscopy." Biophysical Journal 85(3):1826-1838.