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Projects

As a scientific user facility, the Environmental Molecular Sciences Laboratory (EMSL) provides expertise, instrumentation, and resources to 250 projects each year. 

EMSL projects displayed on the EMSL web site project page reflect project abstracts and information migrated to this page before April 30, 2024. To review current and past EMSL user projects, visit EMSL Science Central.™ 

 

  • Projects beginning at or after given date.
    Projects ending at or before given date.

Genomes-to-Life Protein Complex Isolation Capability

Lead Institution
Western University of Health Sciences
Principal Investigator
Thomas Squier
Project type
Exploratory Research
We have established a pilot proteomics facility in support of the "Goal 1" of the Department of Energy's Genomes to Life program, which seeks to identify 80% of the protein complexes…

Site-specific spectroscopy and optical imaging.

Lead Institution
Bowling Green State University
Principal Investigator
H. Peter Lu
Project type
Exploratory Research
To obtain chemical and biological characterization at nanoscale using fluorescence and Raman spectroscopy and imaging.

AFM-enhanced FLIM and Raman imaging.

Lead Institution
Bowling Green State University
Principal Investigator
H. Peter Lu
Project type
Exploratory Research
Metallic AFM tip enhanced spectroscopy will be developed and applied to study chemical process and biological process.

Protein-protein interaction dynamics.

Lead Institution
Bowling Green State University
Principal Investigator
H. Peter Lu
Project type
Exploratory Research
Protein-protein interaction dynamics is highly complex and inhomogeneous. Single molecule spectroscopy will be applied to study these complex interactions one molecule at a time.

Microbial Cell Analysis and Imaging

Lead Institution
Bowling Green State University
Principal Investigator
H. Peter Lu
Project type
Exploratory Research
Using state-of-the-art spacial and temporal optical imaging microscopy to study shewanella cells.

Ion Channel Protein Dynamics in Lipid Bilayer

Lead Institution
Bowling Green State University
Principal Investigator
H. Peter Lu
Project type
Exploratory Research
Voltage controlled protein ion channel in lipid bilayer will be studied by using patch-clamp confocal fluorescence imaging microscopy and single molecule spectroscopy.

Uranium Immobilization by Sulfate-Reducing Biofilms

Lead Institution
Washington State University
Principal Investigator
Haluk Beyenal
Project type
Exploratory Research
In our previous study (Beyenal et al., 2003) we have investigated uranium immobilization by sulfate reducing biofilms and found that sulfate reducing biofilms can successfully immobilize uranium for…

Proteomics of Filamentous Fungi

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Ellen Panisko
Project type
Exploratory Research
As part of the PNNL Biobased Products Initiative, an LDRD proposal entitled “Proteomics of Filamentous Fungi” was funded. In this proposal we outline a broad research plan across the sprectrum of…

PNNL Facilities Master Plan

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Michael Perkins
Project type
Exploratory Research
This project is to support the laboratories effort in planning future facilities at PNNL. I will be developing several architectural renderings to be use in public relations and engineering…

A Variable Energy Electron Mibrobeam

Lead Institution
NASA Ames Research Center
Principal Investigator
Marianne Sowa
Project type
Exploratory Research
A variable energy electron microbeam has been developed and is being utilized for various biological studies.

Syntheses of Fe-S Cluster Complexes with Peptides as Terminal Ligands

Lead Institution
Washington State University Tri-Cities
Principal Investigator
You-jun Fu
Project type
Exploratory Research
Fe-S clusters are active centers of Fe-S proteins acting as electron transfer and storage agents. Fe-S cluster complexes with simple terminal ligand have been studied extensively. We are going to…

Sustrate Identification for Ser/Th Protein Phosphatase

Lead Institution
Purdue University
Principal Investigator
Sandra Rossie
Project type
Exploratory Research
I am interested in the structure, regulation and function of the Ser/Thr protein phosphatase, PP5. We purified this enzyme several years ago based on lipid-activated phosphatase activity. Several…

Nanotemplated Electrodeposition

Lead Institution
University of Washington
Principal Investigator
Daniel Allred
Project type
Exploratory Research
We hope to demonstrate the general use of electrodeposition as a tool for creating nanometer scale patterns using nanoscale surfaces and templates.