Projects

Subsurface Reductive Elimination of Trichloroethylene using Zero-Valent Iron Emplaced by Polymer Solutions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Michael Truex

Project type

Large-Scale EMSL Research

Zero-valent iron (ZVI) has been used for in situ remediation of inorganic compounds and chlorinated solvents through engineered permeable reactive barriers and injectable ZVI particles. A key aspect…

Role of Surface and Interface on Transport Properties in Nanoscale Conducting Oxides

Lead Institution

University of South Carolina

Principal Investigator

Xiao-dong Zhou

Project type

Large-Scale EMSL Research

Size-dependent (&#8804;50 nm) chemical and physical properties of electronic materials have been attributed to primarily either intrinsic contributions, such as changes in the lattice energy and…

Material Homogeneity Studies on 3D Microfabricated Ceramic Structures Using Nanoparticle Building Blocks

Lead Institution

Oregon State University

Principal Investigator

Sundar Atre

Project type

Large-Scale EMSL Research

Nanoparticles are required for both geometric and performance attributes in numerous microscale applications. Curiously, numerous synthesis routes for nanoscale powders have been reported yet…

Characterizing the Composition, Morphology and Reactivity of Bacterial Nanowires using Advanced Scanning Probe Microscopy, MS-Based Proteomics and Scanning Electron Microscopy

Lead Institution

J. Craig Venter Institute

Principal Investigator

Yuri Gorby

Project type

Large-Scale EMSL Research

This project seeks to investigate the composition, morphology and reactivity of electrically conductive appendages known as bacterial nanowires. The research will capitalize on numerous analytical,…

Modeling Multiscale-Multiphase-Multicomponent Subsurface Reactive Flows using Advanced Computing

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Glenn Hammond

Project type

Large-Scale EMSL Research

During the course of the project we will apply PFLOTRAN to uranium migration at the Hanford 300 Area and to CO2 sequestration in subsurface geologic formations. In addition, we will test new…

Conformational Dynamics of Pin1 Regulation of APP processing and Abeta Production

Lead Institution

Cornell University

Principal Investigator

Linda Nicholson

Project type

Large-Scale EMSL Research

The proposed studies fall within the EMSL science theme of "Biological Interactions and Dynamics", specifically in the effort to understand how the "readout", or experimentally…

Mechanistic Studies of Protein Allostery at the Atomistic Scale

Lead Institution

University of California, Berkeley

Principal Investigator

Jhih-Wei Chu

Project type

Large-Scale EMSL Research

Allostery refers to the change of protein conformation in response to ligand binding, biochemical modifications, or interactions with other proteins. In this proposal, we plan to study protein…

STRUCTURAL STUDIES OF REGULATORS OF HISTONE PROTEIN SYNTHESIS

Lead Institution

University of North Carolina

Principal Investigator

Roopa Thapar

Project type

Large-Scale EMSL Research

STRUCTURAL STUDIES OF REGULATORS OF HISTONE PROTEIN SYNTHESIS. Roopa Thapar and William F. Marzluff In each cell cycle a eukaryotic cell must not only replicate its DNA, but must also…

The Aerosol Modeling Testbed

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jerome Fast

Project type

Large-Scale EMSL Research

An Aerosol Modeling Testbed will be developed that will simplify and greatly increase the efficiency of evaluating new aerosol treatments for regional and global climate models. The Aerosol Modeling…

Coupled Hydrological and Geochemical Studies on Uranium Plumes at Hanford Site: Reactions, Spatial Distributions, Speciation, and Future Mobility

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Zheming Wang

Project type

Large-Scale EMSL Research

Massive quantities (exceeding 85 tons) of U currently reside in the Hanford vadose zone, and will threaten groundwater and the accessible environment for generations to come. Present insufficient…

Interfacial Phenomena in Cu Plating

Lead Institution

eMAT Technology LLC

Principal Investigator

Valery Dubin

Project type

Large-Scale EMSL Research

Electroplated Cu on a physical vapor deposited (PVD) Cu seed layer with a PVD Ta-based barrier is now an integrated process for the production of advanced interconnects for integrated circuits (IC),…

Mechanisms of Ubiquitin Transfer and Regulation

Lead Institution

University of Washington

Principal Investigator

Rachel Klevit

Project type

Large-Scale EMSL Research

Protein ubiquitination is a powerful regulatory process that influences nearly every aspect of eukaryotic cell biology. Pathways ranging from cell-cycle progression and differentiation to DNA repair…

Exploring the Proteome of E. coli Following Adaptation to Environmental and Genetic Perturbation

Lead Institution

University of California, San Diego

Principal Investigator

Bernhard Palsson

Project type

Large-Scale EMSL Research

Microorganisms rapidly adapt to changes in the environment which ensures their survival under suboptimal conditions. It is well known that microorganisms display genomic plasticity that enables…

Experimental and Theoretical Investigations on the
Chemistry and Dynamics of Ammonia Borane Dehydrogenation

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Thomas Autrey

Project type

Large-Scale EMSL Research

Increasing demands for clean energy sources that do not add CO2 and other pollutants to the environment have resulted in increased worldwide interest in the possibilities of a "hydrogen economy…

43Ca NMR Spectroscopy of Ca2+ Dependent Proteins and models

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Paul Ellis

Project type

Large-Scale EMSL Research

We are exploring the application and utility of low temperature solid-state NMR methods to the observation of 43Ca in Ca2+ dependent proteins. Our first application is to the protein calbindin D9k …

Advances in Understanding Electron Transfer Kinetics at Environmental Interfaces

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kevin Rosso

Project type

Large-Scale EMSL Research

This EMSL user proposal requests a continuation of EMSL access for a BER funded Environmental Molecular Sciences Institute (EMSI) project led by Dr. Rosso at PNNL. This project constitutes the PNNL…

Determination of Saturation-Capillary Pressure Relations of Crude Oil-Brine Systems to Estimate Oil-Water Interfacial Areas

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Lirong Zhong

Project type

Large-Scale EMSL Research

Effects of salinity on oil recovery and residual oil saturation formation during water flooding are of particular interest for the petroleum industry. Empirical observations indicate that residual…

Development of Time-Dependent Quantum Reaction Dynamics for Surface Reactions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Eric Bylaska

Project type

Large-Scale EMSL Research

We propose to develop multi-dimensional, state-of-the-art time-dependent quantum dynamics (TDQD) computational methods for catalytic surface reactions. Our aim is to obtain accurate initial-state…

Development of 1st principles dynamics with exact exchange and spin-orbit ZORA

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Eric Bylaska

Project type

Large-Scale EMSL Research

1st principles methods of dynamical simulation will be developed that can treat the complex chemistry of actinide elements. In developing new solvers, emphasis will be placed on methods that will…

Characterizing the effects of iron- and sulfate-reduction on aquifer mineralogy: Linking
geophysics and geomicrobiology

Lead Institution

Lawrence Berkeley National Laboratory

Principal Investigator

Kenneth Williams

Project type

Large-Scale EMSL Research

This proposal seeks to provide a quantitative understanding of the mineralogical changes accompanying stimulated iron- and sulfate-reduction during contaminant remediation of uranium and chromium…