Projects

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Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Albert Mendoza

Project type

Exploratory Research

I need data from a glass sample

Accumulation of chromium in Shewanella oneidensis MR-1

Lead Institution

Washington State University

Principal Investigator

Sridhar Viamajala

Project type

Exploratory Research

Objective : The objective of this project is to look at the final products obtained after biotransformation of chromate. We hypothesize that chromate is reduced to insoluble chromium hydroxide and…

Quantitative Measurements in Scattering Media: Path length Determination of Short Wavelength Near Infrared Light in Fish Tissue

Lead Institution

Eastern Oregon University

Principal Investigator

Anna Cavinato

Project type

Exploratory Research

The objective of this study is to understand and evaluate how near infrared light penetrates through fish tissue. This fundamental study is necessary to improve the application of near infrared…

Oxygen versus Iron Terminations in Hematite Basal Surfaces: STM imagin in air and in aqueous solutions.

Lead Institution

Georgia Institute of Technology

Principal Investigator

Andrew Stack

Project type

Exploratory Research

This project will focus on determining the surface structure of hematite basal planes in aqueous solutions. Prior to this writing this proposal, we have been imaging hematite surfaces in solution…

Oxygen versus Iron Terminations in Hematite Basal Surfaces: STM imagin in air and in aqueous solutions.

Lead Institution

Georgia Institute of Technology

Principal Investigator

Andrew Stack

Project type

Exploratory Research

This project will focus on determining the surface structure of hematite basal planes in aqueous solutions. Prior to this writing this proposal, we have been imaging hematite surfaces in solution…

Influence of Calcium Carbonate Coatings on Contaminant Reactivity

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Timothy Droubay

Project type

Exploratory Research

Determine the effects of carbonate coatings on electron transfer reactions responsible for the reduction of chromate with iron oxides. This program utilizes the following methods or techniques:1)…

Whole genome cloning and expression of Treponema pallidum open reading frames

Lead Institution

Baylor College of Medicine

Principal Investigator

Timothy Palzkill

Project type

Exploratory Research

Treponema pallidum is a spirochete bacterium and is the causitive agent of syphilis. The complete genome sequence of T. pallidum is known. The organism has a genome size of 1.1 Mb and encodes 1031…

Isolation and Characterization of Novel Antimicrobial Peptides from the Zebrafish, Danio rerio

Lead Institution

University of Maine

Principal Investigator

Carol Kim

Project type

Exploratory Research

Antimicrobial peptides have been isolated and characterized from a wide variety of organisms. Playing a major role in innate immune defense, antimicrobial peptides have been shown to be capable of…

The proteome of prostate cancer-derived exosomes: Exosomes as biomarker treasure chests

Lead Institution

Erasmus University Medical Center, Rotterdam

Principal Investigator

Guido Jenster

Project type

Large-Scale EMSL Research

Prostate cancer (PCa) is the most common cancer and the second leading cause of cancer death in men. Although considerable progress in the clinical setting has been made in the past decades, early…

Solid-State NMR Structural Studies of HIV-1 CA Protein Assembly

Lead Institution

University of Delaware

Principal Investigator

Tatyana Polenova

Project type

Large-Scale EMSL Research

This is an application in response to the proposal call "Science Theme: Biological Interactions and Dynamics". We request standard, general non-proprietary access to the 900 MHz solid-state…

Mechanisms of nanocrystalline uraninite oxidation by iron minerals under of sulfate-reducing bacteria

Lead Institution

South Dakota School of Mines and Technology

Principal Investigator

Rajesh Sani

Project type

Large-Scale EMSL Research

Uranium (U) is the most common radionuclide in soils, sediments, and groundwater at many sites including U.S. DOE sites and is therefore of particular environmental concern. Subsurface bacteria such…

Comprehensive Analysis Of Post-Translational Modifications (PTMs) In Proteins Involved In Histone Pre-mRNA Processing By High Performance nanoLC-MS

Lead Institution

University of North Carolina

Principal Investigator

Roopa Thapar

Project type

Large-Scale EMSL Research

All eukaryotic mRNAs undergo a series of posttranscriptional processing events that lead to the generation of a mature mRNA transcript which is then translated. These pre-mRNA processing steps…

Structural basis of the lysis clock in bacteriophages: the holin-antiholin interaction of phage lambda

Lead Institution

Texas A&M University

Principal Investigator

Christian Hilty

Project type

Large-Scale EMSL Research

Bacteria are the most abundant organisms in the biosphere, and, after cell division, the second most common fate of bacterial cells is lysis by bacteriophage. For most bacteriophages, the duration…

Proteomic Analysis of Extracellular Appendages Displayed in Desulfovibrio vulgaris

Lead Institution

Oak Ridge National Laboratory

Principal Investigator

Dwayne Elias

Project type

Large-Scale EMSL Research

Sulfate-reducing bacteria makeup a substantial portion of subsurface microbial communities at DOE contaminated sites in particular. They are capable of reducing and immobilizing, soluble U(VI) by…

Phosphoproteomic profiling of breast cancer cell lines

Lead Institution

Erasmus University Medical Center, Rotterdam

Principal Investigator

Arzu Umar

Project type

Large-Scale EMSL Research

Breast cancer is a very heterogeneous disease, consisting of different molecular subtypes. Effective, targeted treatment is available for estrogen receptor (ER) and human epidermal growth factor…

Abiotic reduction of U(VI) by sorbed Fe(II) and the implications for field-scale bioremediation at the Rifle IFC project site

Lead Institution

US Geological Survey, Menlo Park

Principal Investigator

Kate Campbell

Project type

Large-Scale EMSL Research

Bioremediation of uranium-contaminated sites has recently been explored as a potentially effective groundwater treatment option. The injection of an organic carbon substrate such as acetate…

Simultaneous Optical & Chemical Measurements of Aerosols as a Function of Relative Humidity: Bridging Laboratory and Field Measurements to Models

Lead Institution

Los Alamos National Laboratory

Principal Investigator

Manvendra Dubey

Project type

Large-Scale EMSL Research

Interactions of anthropogenic aerosols with solar radiation and clouds and are the largest source of uncertainty in climate change science. The key science gap is a lack of process-level knowledge…

The Influence of different Fe(III) Phases and the Effect of Sulfate Reduction on the Simultaneous Bioreduction of Iron and Uranium

Lead Institution

Princeton University

Principal Investigator

Peter Jaffe

Project type

Large-Scale EMSL Research

Biostimulation of Fe(III) and/or sulfate reducing microorganisms by addition of acetate can effectively reduce U(VI). However, U(VI) removal from groundwater was hindered in field trials at the…

Probing the Reactivity of Organic Particles Using Ion Soft-Landing

Lead Institution

University of California, Irvine

Principal Investigator

Sergey Nizkorodov

Project type

Large-Scale EMSL Research

Formation and atmospheric processing of particulate matter is one of the focus areas emphasized by EMSL. Organic coatings on atmospheric aerosols determine the surface chemistry that particles…

Scanning and Transmission Electron Microscopy of Grape Berry Shrivel

Lead Institution

Washington State University Tri-Cities

Principal Investigator

Bhaskar Bondada

Project type

Large-Scale EMSL Research

The state of Washington is the second largest producer of premium wine in the nation and is ranked among the worlds top wine regions. Washington wines are found nationally in all 50 states and…