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Christopher Hill

Institution
University of Utah
ORCID
ORCID logo 0000-0001-6796-7740

Projects

Tom1/HUWE1 and its interaction with Spt6

Lead Institution
University of Utah
Principal Investigator
Christopher Hill
Our lab reported that the transcriptional regulator, Spt6, contains a tandem-SH2 domain that binds RNA pol II through a novel interaction that requires multiple phosphorylation site on the Rpb1…

IR-A agonist structures

Lead Institution
University of Utah
Principal Investigator
Christopher Hill
Our goal is to determine the structure of the insulin receptor (IR) ectodomain bound to non-insulin peptide modulators of the receptor. We are studying two peptides that share a high degree of…

Bcs1 Complex

Lead Institution
University of Utah
Principal Investigator
Christopher Hill
Our goal is to determine the structure of heptameric AAA+ ATPase Bcs1 bound to its native substrate Rip1. Rip1 is a critical component of the Complex III of mitochondrial electron transport chain…

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
James Evans
PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

Insulin receptor-peptide agonist structures

Lead Institution
University of Utah
Principal Investigator
Christopher Hill
Our goal is to determine the structure of the insulin receptor (IR) ectodomain bound to non-insulin peptide modulators of the receptor. We are studying two peptides which share a high degree of…

Active Structure of ClpX Bound to SsrA substrate

Lead Institution
University of Utah
Principal Investigator
Christopher Hill
AAA+ ATPases are involved in myriad cellular functions, including cell membrane reformation, chromatin remodeling, protein degradation and quality control. Our lab is investigating the mechanism,…