Xuefei Sun

Microfabrication of Electrospray Emitter Arrays for Improved Sensitivity in Electrospray Ionization-Mass Spectrometry

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

Project type

Large-Scale EMSL Research

Liquid chromatography (LC), combined with mass spectrometry (MS), is an extremely powerful platform for protein analysis, allowing complex mixtures first separated by LC to be further resolved and…

Collaborative Research Projects Supported by the NCRR P41 Resource Center

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

David Camp

Project type

Large-Scale EMSL Research

The Proteomics Resource Center for Integrative Biology at PNNL was established in 2003 and builds on the unique instrumentation and the infrastructure provided by PNNLs EMSL facility. The mission of…

High-Throughput Proteomics: Applications and Development (PNNL Scope #40601 and #43488)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Gordon Anderson

This project involves the application and development of high-throughput proteomics and quantitative measurement capabilities within biological systems. More so, application measurements will be…

Collaborative research projects in the PNNL NIH NCRR P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

David Camp

Collaborative research projects in the PNNL NIH NCRR P41 Biomedical Technology Research Center 'Proteomics research resource for integrative biology'

Microfluidic Devices for Improving Protein Identification and Reducing the Sample Sizes Required for Proteomic Analyses

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

We propose to utilize the EMSL microfabrication facility to create microfluidic devices for improving proteomics analyses. Integrated function microchips will be developed that handle the necessary…

Center for Application of Advanced Clinical Proteomic Technologies for Cancer (NCI U24; 59963)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Tao Liu

The overall objective of the PNNL Clinical Proteome Characterization Center (PCPCC) is to facilitate cancer biomarker development by linking the cancer genotype to the cancer phenotype using detailed…

Pan-Omics Technology Development, Implementation, and Application to GSP Systems Biology Research

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Joshua Adkins

The BER Genome Science Program aims to understand complex biological and environmental systems across spatial and temporal scales to develop predictive knowledge relevant to DOE mission challenges…

Single Cell Analysis Using Microfluidics Coupled to Ultrasensitive Mass Spectrometry

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

Proteomics and metabolomics measurements in their present form require large populations of cells and thus average over and obscure important heterogeneity that is present even in clonal populations…