Lipidomics of circadian rhythm of vascular function in midlife adults
EMSL Project ID
60162
Abstract
The proposed research study is to perform lipidomics analyses on human blood plasma collected from middle aged participants that underwent a 5-day laboratory circadian rhythm study. The laboratory protocol consisted of an initial baseline 8-hour sleep opportunity at the participant’s habitual sleep time and a baseline day followed by 10 identical recurring 5-hour 20-minute sleep/wake cycles (2-hour 40-minute sleep opportunity and 2-hour 40-minute scheduled wakefulness) to desynchronize the scheduled behaviors from the endogenous circadian system while permitting adequate sleep opportunity across all circadian phases. The goal of this study is to profile the blood plasma lipidome and evaluate differences due to circadian rhythm and the role of body mass index (BMI) may have on the lipidome.
Project Details
Start Date
2021-07-21
End Date
2023-10-01
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members