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The National Microbiome Data Collaborative: improving metaproteomics methods and processing capabilities


EMSL Project ID
60205

Abstract

Abstract

We will improve and streamline the metaproteomics analysis workflow used by both EMSL and the NMDC. Generating gold-standard proteomics data will support algorithmic improvements for the inference of protein presence and abundance from peptide-level mass spectrometry data, and streamlining the metagenome curation prior to proteomics data processing will constrain the search space used for peak matching.

Project Details

Start Date
2021-08-25
End Date
2023-10-01
Status
Closed

Team

Principal Investigator

Lee Ann McCue
Institution
Environmental Molecular Sciences Laboratory

Team Members

Jordan Rabus
Institution
Pacific Northwest National Laboratory

Fnu Anubhav
Institution
Pacific Northwest National Laboratory

Yuri Eberlim de Corilo
Institution
Environmental Molecular Sciences Laboratory

Montana Smith
Institution
Environmental Molecular Sciences Laboratory

Paul Piehowski
Institution
Environmental Molecular Sciences Laboratory

Samuel Purvine
Institution
Environmental Molecular Sciences Laboratory

Mary Lipton
Institution
Environmental Molecular Sciences Laboratory