Yuri Eberlim de Corilo | Environmental Molecular Sciences Laboratory

The National Microbiome Data Collaborative: improving metaproteomics methods and processing capabilities

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Paul Piehowski

We will improve and streamline the metaproteomics analysis workflow used by both EMSL and the NMDC. Generating gold-standard proteomics data will support algorithmic improvements for the inference of…

Increased confidence, coverage, and characterization of organic matter through online liquid chromatography hybrid FT-Orbitrap-21T ICR mass spectrometry

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

William Kew

Direct infusion (DI) mass spectrometry analysis of organic matter (OM) is one of EMSL’s primary workflows. It is a powerful and popular means to characterize complex environmental samples. However,…

Identifying and Quantifying Sources of Variability in FTICR

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Allison Thompson

Many EMSL users are requesting Fourier transform ion cyclotron resonance (FTICR) soil organic matter (SOM) data. However, there are many circumstances where results are unexpected and experts…

Software Development for High-Resolution Mass Spectrometry Analysis of Small Molecules: Enabling High-Throughput, Reproducible Data Processing and Annotation.

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Yuri Eberlim de Corilo

Modern high-resolution mass spectrometry has dramatically increased the volume (distinct analytical techniques and polarity modes) and quality (higher resolving power, dynamic range, mass error…

Acquisition-Time Quality Control Workflow for FT-ICR MS Complex Mixture Analysis

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Yuri Eberlim de Corilo

High throughput complex mixture analysis is hindered by challenges in automating data acquisition, namely ensuring that the data generated is of consistently high quality as required for automatic…

High Confidence Characterization of Organohalogen & Organometallic Compounds by Orthogonal LC-ICP and LC-HR Mass Spectrometry

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Yuri Eberlim de Corilo

Interactions between metals, halogens, and other elements are critical regulators of organic matter transport, persistence, and toxicity. Still, they remain poorly characterized due to the samples&…

Centralized Metabolomics Molecular Reference Database

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Yuri Eberlim de Corilo

Reference databases, both in-silico and molecular standard-based, are vital components in all metabolomics data annotation workflows. However, these databases are often decentralized or have…

1000 Soils Research Campaign

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Nancy Hess

Project type

MONet

To more fully understand the cycling of carbon, carbon-based nutrients and key elements from the molecular to basin scale across variations in soil chemistry, the Environmental Molecular Sciences…

The National Microbiome Data Collaborative: improving metaproteomics methods and processing capabilities

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Lee Ann McCue

We will improve and streamline the metaproteomics analysis workflow used by both EMSL and the NMDC. Generating gold-standard proteomics data will support algorithmic improvements for the inference of…

Online, real-time instrument parameter optimization for FT-ICR mass spectrometry

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

William Kew

Optimal and efficient use of FT-ICR mass spectrometers is a critical step to high-throughput and automated analyses, as well as for ensuring the highest fidelity of data and scientific rigor. This…

MONet Data Management and Access Gateway

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Yuri Eberlim de Corilo

We will develop, implement, and deploy the backend software necessary to manage, store, and serve as the gateway to make the MONet data findable, accessible, interoperable, and reusable (FAIR). In…

Projects