The National Microbiome Data Collaborative: improving metaproteomics methods and processing capabilities
EMSL Project ID
61033
Abstract
We will improve and streamline the metaproteomics analysis workflow used by both EMSL and the NMDC. Generating gold-standard proteomics data will support algorithmic improvements for the inference of protein presence and abundance from peptide-level mass spectrometry data, streamlining the metagenome curation prior to proteomics data processing will constrain the search space used for peak matching, and using observed spectra to train a machine learning model will enable genome reference-free metaproteomics.
Project Details
Start Date
2023-10-20
End Date
N/A
Status
Active
Released Data Link
Team
Principal Investigator
Co-Investigator(s)
Team Members