Projects

Investigation of anaerobic lignocellulose decomposition in Puerto Rico tropical forest soils

Lead Institution

University of Massachusetts Amherst

Principal Investigator

Kristen DeAngelis

Project type

Large-Scale EMSL Research

As one of the primary objectives of the DOE Joint BioEnergy Institute (JBEI), our project aims to identify and characterize unique microorganisms, enzymes and pathways with novel lignocellulolytic…

Transformation Mechanisms and Kinetics of Fe-(oxyhydr)oxide Reduction and their Impact on Uranium Sequestration

Lead Institution

Stanford Linear Accelerator Center

Principal Investigator

Juan Lezama Pacheco

Project type

Large-Scale EMSL Research

Redox cycling of Fe-(oxyhydr)oxides such as ferrihydrite in naturally or artificially reduced sediments has a major impact on the speciation and stability of uranium. Ferrihydrite is a poorly…

Geobiology of Chemical Weathering: Spatially Explicit Characterization of the Inorganic Chemical Composition of Mycorrhizospheric Biofilms

Lead Institution

Washington State University

Principal Investigator

Chester Keller

Project type

Large-Scale EMSL Research

Rich literatures and recent advances across several fields have set the stage for process-based research into the biogeochemical agency of vascular plants -- in particular, how their physiologies…

The Quaternary Structures of Enamel Proteins at Interfaces Studied by Helium-ion Microscopy (HIM)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Barbara Tarasevich

Project type

Large-Scale EMSL Research

The interactions of proteins at surfaces are of great importance to biomineralizaton processes and to the development and function of biomaterials. Amelogenin is a unique biomineralization protein…

Cell Injury Involving Transmetallation of Gadolinium Based MRI Contrast Agents

Lead Institution

Oregon Health & Science University

Principal Investigator

Wassana Yantasee

Project type

Large-Scale EMSL Research

This EMSL user proposal is directly responsive to Biological Interactions and Dynamics Science Theme. The work involves the fundamental studies on the heterogeneity in cell composition and response…

Ubiquitin Signaling and Bacterial Effector Proteins

Lead Institution

University of Washington

Principal Investigator

Peter Brzovic

Project type

Large-Scale EMSL Research

In plants and animals post-translational modification of proteins by ubiquitin (Ub) is a regulatory process that impacts nearly every aspect of eukaryotic cell biology. Diverse pathways including,…

Fundamental Studies of the Interaction of Pd and Rh Particles with Ceria and Ceria-Zirconia Surfaces in Model Planar atalysts

Lead Institution

University of Michigan

Principal Investigator

Xiaoqing Pan

Project type

Large-Scale EMSL Research

Ceria and ceria-based oxides have been widely investigated as electronic promoters of activity, selectivity, and thermal stability in a variety of catalysts. Pd on ceria-based supports is an…

Molecular Interactions and Dynamics at Solid Electrolyte Interfaces

Lead Institution

State University of New York at Binghamton

Principal Investigator

Howard Wang

Project type

Large-Scale EMSL Research

We will carry out a systematic study on molecular interactions and dynamics at solid electrolyte interfaces (SEIs) of Li-ion batteries using primarily in situ quantitative nonlinear optical…

Molecular-level Investigation of Dissolved and Stabilized Organic Carbon in Soil

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James Amonette

Project type

Large-Scale EMSL Research

Soils contain large amounts of organic carbon (OC) and serve as both sources and sinks for atmospheric C. However, little is known about the structural chemistry of stabilized soil OC or the…

Biomineralization and Biosequestration Mechanisms at Lifes Upper Temperatures: A Reappraisal using Novel CryoEM Techniques

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Sherry Cady

Project type

Large-Scale EMSL Research

Given that (i) hyperthermophilic and thermophilic biofilms were some of the earliest microbial communities to inhabit our planet, (ii) such communities evolved and thrived in heavy metal-rich…

Looking for Partners in Crime: Identification of Protein Complexes and Post-Translational Modifications Associated with Drug-Resistance in Breast Cancer

Lead Institution

Erasmus University Medical Center, Rotterdam

Principal Investigator

Arzu Umar

Project type

Large-Scale EMSL Research

Drug resistance of metastatic tumor cells is the major cause of death in breast cancer patients. Through a previous EMSL collaboration, EMMPRIN (extracellular matrix metalloproteinase inducer) was…

Phosphoproteomics of Nuclear Pore Disassembly and Reassembly during Mitosis

Lead Institution

The Ohio State University

Principal Investigator

Stephen Osmani

Project type

Large-Scale EMSL Research

Eukaryotic cells segregate DNA equally to daughter cells during mitosis. Although mitosis is well characterized, its regulation is still poorly understood. The most extensive and least understood…

Metal-blacks for plasmonic enhancement of solar-cell efficiency

Lead Institution

University of Central Florida

Principal Investigator

Robert Peale

Project type

Large-Scale EMSL Research

Metal-blacks are nano-structured porous metal films that have potential to enhance the efficiency of thin film solar cells via transverse scattering and concentration of the incident electromagnetic…

Growth analysis in mixed microbial populations using microscopy coupled with computational approaches

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Alex Beliaev

Project type

Large-Scale EMSL Research

Microbial phototroph-heterotroph associations (PHA) are common in nature as they provide basis for many water- and terrestrial-based ecosystems. Metabolic interactions between partners are the…

Study of Catalytic Properties of Atomic Gold in Polyaniline

Lead Institution

Georgia Institute of Technology

Principal Investigator

Miraslawa Josowicz

Project type

Large-Scale EMSL Research

Study of Catalytic Properties of Atomic Gold in Polyaniline Project Lead: Mira Josowicz, Ph.D Project Lead Institution: Georgia Institute of Technology, Georgia Tech Research Corporation Abstract…

Surface-Induced Dissociation of Large Molecules in Mass Spectrometry

Lead Institution

Purdue University

Principal Investigator

Julia Laskin

Project type

Large-Scale EMSL Research

The general objective of our research is to achieve a fundamental understanding of the reaction kinetics and dynamics of activating and dissociating complex molecular ions, develop molecular level…

Assembly of the mRNA 3'-end processing machinery

Lead Institution

University of Washington

Principal Investigator

Gabriele Varani

Project type

Large-Scale EMSL Research

We propose to use NMR to study the structural basis for the assembly of the protein complex responsible for the formation of mature 3'-ends of mRNAs by cleavage and polyadenylation, and the…

Exploring Microbe-Microbe and Microbe-Environment Interactions in Acidiphilium cryptum and Acidithiobacillus ferrooxidans: A Model Contaminant Metal Redox Cycling System

Lead Institution

Idaho State University

Principal Investigator

Timothy Magnuson

Project type

Large-Scale EMSL Research

Dissimilatory metal-respiring bacteria (DIRB) of widely differing phylogenetic and ecophysiologic affiliation share one distinct physiologic feature-the copious production of redox-active…

Laboratory Studies of the Role of Amines in Particle Formation, Growth and Climate

Lead Institution

University of California, Irvine

Principal Investigator

Barbara Finlayson-Pitts

Project type

Large-Scale EMSL Research

Understanding the processes involved in new particle formation (NPF) and growth in the atmosphere is critical for accurate predictions of their impacts on visibility, climate and health. Recent…

Estimation of lifetime and evaluation of (Co,Mn)3O4 coatings for IT-SOFC Steel Interconnects application by determining of Cr and O diffusion coefficients

Lead Institution

Western Michigan University

Principal Investigator

Asghar Kayani

Project type

Large-Scale EMSL Research

Intermediate temperature solid oxide fuel (IT-SOFC) are becoming increasingly attractive as a way of producing energy from a variety of fuels such as hydrogen and hydrocarbons, which can be used for…