Projects

MITOTIC REGULATION OF THE NUCLEAR PORE COMPLEX PROTEIN INTERACTION NETWORK

Lead Institution

The Ohio State University

Principal Investigator

Stephen Osmani

Project type

Large-Scale EMSL Research

Eukaryotic cells segregate DNA equally to daughter cells during mitosis. Although mitosis is well characterized, it is poorly understood at the molecular level. The most extensive and least…

A proteomic investigation of changes in lipid droplet-bound proteins

Lead Institution

University of California, Irvine

Principal Investigator

Steven Gross

Project type

Large-Scale EMSL Research

Lipid droplets are the body's major location for storing fat to be later used as energy. As such, understanding the regulated function of these droplets is an essential part of understanding…

Hydrogen Production-(Steam Reforming of hydrocarbons including methane, propane, gasoline, jet fuel and biomass derived products)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Robert Dagle

Project type

Large-Scale EMSL Research

Hydrogen Production-(Steam Reforming of hydrocarbons including methane, propane, gasoline, jet fuel and biomass derived products)

Nanomaterials for Chelation Therapies and Sensing Applications

Lead Institution

Oregon Health & Science University

Principal Investigator

Wassana Yantasee

Project type

Large-Scale EMSL Research

The self-assembled monolayer on mesoporous support (SAMMS) materials, functionalized magnetic nanoparticles, and carbon nanotubes are three emerging important nanomaterials that have many promising…

Platelet proteome for normal and type-2 diabetics

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

David Springer

Project type

Large-Scale EMSL Research

Abstract Our proposal entitled "Platelet proteome for normal and type-2 diabetics" is funded by NIH through an R21 grant. The research is designed to characterize the proteome from human…

Chemical Kinetics and Dynamics at Interfaces: Structure and Reactivity of Ices, Amorphous Solids, and Supercooled Liquid Solutions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

R. Smith

Project type

Large-Scale EMSL Research

This proposal is a continuation of research under EMSL User Proposal #21890. The objective of this research is to examine physiochemical phenomena occurring at the surface and within the bulk of…

Ion Beam Implantation of Titanium Alloys to Improve Durability in Structural and Biomedical Applications

Lead Institution

Colorado School of Mines

Principal Investigator

Kip Findley

Project type

Large-Scale EMSL Research

Titanium alloys with high strength-to-weight ratios have vast potential in the automotive, aerospace, and biomedical fields. The automotive and aerospace industries are seeking more fuel efficient…

Instrument Testing and Deployment for the DOE CHAPS Field Campaign

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Carl Berkowitz

Project type

Large-Scale EMSL Research

We are requesting support for EMSL participation in DOEs Cumulus Humilis Aerosol Plume Study, CHAPS. This campaign is being organized by DOEs Atmospheric Sciences Program (ASP) with support from NOAA…

Collaborative Research Projects Supported by the NCRR P41 Resource Center

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

David Camp

Project type

Large-Scale EMSL Research

The Proteomics Resource Center for Integrative Biology at PNNL was established in 2003 and builds on the unique instrumentation and the infrastructure provided by PNNLs EMSL facility. The mission of…

The Effects of gamma-Irradiation on the Fe(II)/Fe(III) Signatures in Iron Oxide and Iron Silicate Minerals

Lead Institution

University at Buffalo, State University of New York

Principal Investigator

Tracy Bank

Project type

Large-Scale EMSL Research

In our previous study of the effects of gamma-irradiation (sterilization) on natural sediments containing Fe(III)-oxides, Mn-oxides, Fe-rich clay and quartz minerals, analyses showed that cation…

Microbiological, Geochemical and Hydrologic Processes Controlling Uranium Mobility: An
Integrated Field-Scale Subsurface Research Challenge Site at Rifle, Colorado

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Ravi Kukkadapu

Project type

Large-Scale EMSL Research

The U.S. DOE faces the challenge of cleaning up and/or monitoring large, dilute plumes contaminated by metals, such as U, Tc and Cr, whose mobility and solubility change with redox status. At the…

Heterogeneous Uptake of HNO3 on CaCO3: Determination of the Gas-Particle Reaction Probability as Function of Relative Humidity

Lead Institution

University of Iowa

Principal Investigator

Vicki Grassian

Project type

Large-Scale EMSL Research

The proposed work will provide an accurate measurement of the heterogeneous reaction probability for HNO3 on CaCO3 and its dependence on relative humidity. The value of &#947;HNO3 (uptake…

Reduction of Technetium by Fe(II) associated with reduced clay mineral nontronite

Lead Institution

Miami University

Principal Investigator

Hailiang Dong

Project type

Large-Scale EMSL Research

Because clay and clay-like minerals are commonly present at DOE sites (smectite, illite, chlorite, biotite), and they are potential backfill materials for nuclear waste repositories, the interaction…

Characterization of Bio-inspired Photonic Crystals for Enhancing Solar Energy Conversion by Single-Molecule Spectroscopy

Lead Institution

Oregon State University

Principal Investigator

Greg Rorrer

Project type

Large-Scale EMSL Research

Currently, there is a need for more efficient and cost-effective conversion of solar energy to electricity. The efficiency of photovoltaic solar cells is compromised by the mismatch between the…

Michael Knoblauch's Proposal
Molecular Structure and Interaction of Forisome Filaments

Lead Institution

Washington State University

Principal Investigator

Michael Knoblauch

Project type

Large-Scale EMSL Research

Emerging technologies are creating increasing interest in smart materials that may serve as actuators in micro- and nanodevices. Mechanically active polymers currently studied include a variety of…

Impact of Reactive Halogen Species on the Air Quality in Southern California Coastal Areas

Lead Institution

Washington State University

Principal Investigator

Bertram Jobson

Project type

Large-Scale EMSL Research

Air pollution in coastal urban centers remains one of the most serious environmental challenges in the State of California, and further efforts to improve air quality are a priority. Mitigation…

Analysis of Organic Oligomers Forming Secondary Aerosol from Wood Combustion-Derived Phenols

Lead Institution

University of California, Davis

Principal Investigator

Cort Anastasio

Project type

Large-Scale EMSL Research

Aqueous reactions of phenols will be studied in the laboratory using well defined solutions over a range of conditions (e.g., phenol mixture, oxidant and pH) as surrogates for atmospheric drops. The…

Location of Probes in Membrane and Model Membrane Systems and Their Effects on Lipid Reorangization

Lead Institution

Colorado State University

Principal Investigator

Debbie Crans

Project type

Large-Scale EMSL Research

This proposal investigate how probes and metal complexes interact with lipid interfaces by studying location and their interaction with lipid interfaces as a launching point for studies relating to…

High Resolution Fourier Transform Infrared Spectroscopy Studies of Multidimensional H Transfer in Tropolone/Tropolonoid Molecules-a Bridge to the Behavior in Biological Systems

Lead Institution

Texas Technical University

Principal Investigator

Richard Redington

Project type

Large-Scale EMSL Research

In the year 2000 high resolution infrared spectroscopy experiments conducted in EMSL at PNNL were initiated on the nonrigid gaseous tropolone molecule (2-hydroxy-2,4,6-cycloheptatrien-1-one). On the…

Fabrication of a Carbon Nanotube Thermionic Cathode

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kyle Bunch

Project type

Large-Scale EMSL Research

We propose to fabricate a thermionic cathode based on carbon nanotubes as an emitting material. Electron sources compatible with microfabrication processes are critical for the advancement of…