Projects

Structural Engineering of the de novo Designed Protein Top7 as
a Scaffold for Antigen-binding

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Cheryl Baird

Project type

Large-Scale EMSL Research

Deployable biosensors for detecting environmental contaminants at the source require molecular sensing elements or affinity reagents that can survive the fluctuations in temperature and complex…

Surface and Bulk Characterization of Ambient Ultrafine Particles

Lead Institution

Central Washington University

Principal Investigator

Anne Johansen

Project type

Large-Scale EMSL Research

The ultrafine fraction of airborne particulate matter (UFP's - < 100 nm diameter) have been shown to cause significant oxidative stress and damage to mitochondrial membranes. Since this size…

Surface Characterization of Calcium Phosphates

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Wendy Shaw

Project type

Large-Scale EMSL Research

Heterogeneous nucleation is important in the development of biominerals such as bone, teeth and mollusk shells, but often, initial nucleation events are not understood at a mechanistic level(1). It…

Structure-function correlations of proteins in enamel formation

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Wendy Shaw

Project type

Large-Scale EMSL Research

Heterogeneous nucleation is important in the development of biominerals such as bone, teeth and mollusk shells, but often, initial nucleation events are not understood at a mechanistic level. It is…

Solid-State NMR Spectroscopy on Radioactive Samples with Microcoils

Lead Institution

CEA Saclay

Principal Investigator

Dimitris Sakellariou

Project type

Large-Scale EMSL Research

The first phase of this project will be concerned with the development of a novel NMR detector based on the microcoil designs of the CEA-Saclay solid-state NMR group. The successful implementation…

Mixed Oxide Films for gas sensing and photo-catalytic applications

Lead Institution

Wayne State University

Principal Investigator

Karur Padmanabhan

Project type

Large-Scale EMSL Research

The proposed research is a joint effort between WSU and EMSL laboratory at PNNL to study mixing between specific oxide-oxide systems and understand the mixing mechanisms under 2 different…

Local structure in zirconia-based nuclear fuels and transmutation targets

Lead Institution

University of Cambridge

Principal Investigator

Ian Farnan

Project type

Large-Scale EMSL Research

A programme of work is proposed to understand local ordering in inert matrix nuclear fuels based on yttria-stabilized zirconia (YSZ). This information is unobtainable using diffraction techniques…

Spin Electronic Phenomena in Magnetically Doped Perovskites and Complex Oxide Interfaces

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Scott Chambers

Project type

Large-Scale EMSL Research

Semiconductor spintronics has the potential to create entirely new paradigms for analog and digital electronics which may have a significant impact on energy consumption and efficiency. However,…

Soft-Landing of Complex Ions on Surfaces

Lead Institution

Purdue University

Principal Investigator

Robert Cooks

Project type

Large-Scale EMSL Research

Interaction of ions with surfaces is an area of active fundamental research in surface science relevant to a broad range of other scientific disciplines supported by the DOE Office of Science such as…

Molecular-level understanding of transport and optic properties of doped oxide nanoclusters

Lead Institution

University of Idaho

Principal Investigator

You Qiang

Project type

Large-Scale EMSL Research

In this proposal, a research plan to investigate ferromagnetic zinc oxide (ZnO) nanoclusters is outlined. ZnO is a widely studied material due to its wide-band gap energy of 3.3 eV at room…

Molecular Dynamics Study of an Actin Septamer: Testing the Holmes Model and the Hydrophobic Plug Loop Hypothesis

Lead Institution

Northwestern University

Principal Investigator

George Schatz

Project type

Large-Scale EMSL Research

This proposal is in response to the Science Theme Call. We are requesting standard access with non-proprietary status. Actin is a cellular protein which polymerizes into helical filaments. These…

Substrate-specific binding of Staphylococcus adhesins to solid surfaces

Lead Institution

The Ohio State University

Principal Investigator

Steven Lower

Project type

Large-Scale EMSL Research

A nearly universal trait of bacteria is their ability to attach to solid surfaces. Attached cells often form biofilms that are implicated in a significant amount of human infections and have been…

Quorum Sensing in a Dissimilatory Metal Reducing Bacterium

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Michael Hochella

Project type

Large-Scale EMSL Research

Quorum sensing is a versatile regulatory mechanism exhibited by several members of Bacteria. Even though this area of research is a rapidly growing field with clear environmental applications, it…

Raman Capability for EMSL Users

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Nancy Hess

Project type

Large-Scale EMSL Research

Currently users of the EMSL facility do not have access to a to a dedicated Raman system. The objective of this proposal is to establish a usage agreement between the Environmental Spectroscopy…

Molecular Level Construction of Functional Surfaces

Lead Institution

New Jersey Institute of Technology

Principal Investigator

Sergiu Gorun

Project type

Large-Scale EMSL Research

The objective of the proposed work is to develop procedures for molecular level construction of layers of hybrid organic inorganic composites exhibiting divergent, but useful properties. Examples of…

Chemistry of Aerosols in Mexico City: MILAGRO 2006 study.

Lead Institution

Lawrence Berkeley National Laboratory

Principal Investigator

Mary Gilles

Project type

Large-Scale EMSL Research

The MILAGRO (Megacity Initiative: Local and Global Research Observations) Campaign in Mexico City 2006 was a collaborative effort with the DOE Atmospheric Science Program, the NSF MIRAGE-Mex field…

Chemical and Physical Properties of Biomass Burning Aerosol

Lead Institution

Colorado State University

Principal Investigator

Jenny Hand

Project type

Large-Scale EMSL Research

Biomass burning is one of the most important single sources of carbonaceous particles emitted into atmosphere mostly as a result of wilderness fires. Biomass burning aerosols (BBA) have dramatic…

Selective Heterogeneous Catalysis

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Leonard Fifield

Project type

Large-Scale EMSL Research

(Abstract from PNNL Lab Fellows LDRD proposal) [In this project we will create a "single site" catalysis capability at PNNL by robustly tethering catalytic centers to surfaces . The …

NMR and Computational Studies of Chemical Transformations at Complex Interfaces

Lead Institution

University of Alabama

Principal Investigator

David Dixon

Project type

Large-Scale EMSL Research

Catalysis provides the means of controlling the rates at which chemical bonds are formed or broken and the yields of desired products over undesired ones. New computational and experimental…

Ion Beam Analysis of Components for Solid Oxide Fuel Cells

Lead Institution

Montana State University

Principal Investigator

Richard Smith

Project type

Large-Scale EMSL Research

The objective of the proposed research is to develop components for solid oxide fuel cells (SOFCs) that will withstand the corrosive operating environment of the cell (800 oC, atmosphere of hydrogen,…