Projects

Structure, Composition, and Phase Behavior of Mixed Biphenylthiol Self-Assembled Monolayers

Lead Institution

Central Washington University

Principal Investigator

Eric Bullock

Project type

Large-Scale EMSL Research

Controlling nanoscale surface and interface properties is of high interest in molecular electronics, sensors, biocompatible materials, and many other fields. One route to such surface…

OCD_Identification of Potential Plasma Biomarkers for Insulin Resistance Using Proteomics

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Joel Pounds

Project type

Exploratory Research

Insulin resistance is a prevalent medical condition that accompanies type 2 diabetes, obesity, hypertension, metabolic syndrome, and polycystic ovary disease. The insulin-resistant state has been…

Investigation of Dynamics of Villin Headpiece Subdomain by Solid-State NMR with the Use of Single-Site Labeling.

Lead Institution

University of Alaska at Anchorage

Principal Investigator

Liliya Vugmeyster

Project type

Large-Scale EMSL Research

Villin headpiece protein subdomain (HP36) is extensively used as a model system for protein folding. A mutation of F58 residue was shown to rupture the native fold. Yet a double mutant involving two…

Single Particle Laboratory Studies of Heterogeneous Reactions of Trace Atmospheric Gases with Particles Present in the Troposphere

Lead Institution

University of Iowa

Principal Investigator

Vicki Grassian

Project type

Exploratory Research

It is becoming increasingly clear that heterogeneous processes involving particulate matter in the atmosphere can greatly perturb the chemical composition of both the troposphere and the…

Resonant surface excitation of Potassium salts by selective laser desorption

Lead Institution

Mary Baldwin College

Principal Investigator

Margaret Ankney

Project type

Exploratory Research

The objective of the proposed research is to lead to an understanding of some of the relaxation mechanisms of electronically excited states on ionic surfaces. This will be accomplished through…

TEM study of strontium bismuth niobate ferroelectric ceramics doped with vanadium and tungsten oxides

Lead Institution

University of Washington

Principal Investigator

Guozhong Cao

Project type

Exploratory Research

Recent we have studied the incorporation of vanadium and tungsten into layer-structured perovskite ferroelectric strontium bismuth niobate ceramics. Our study revealed significantly enhanced remanent…

Fourier Transform Infrared Spectroscopy and Temperature Program Desorption(TPD) studies of Amorphous Solid Water(ASW)as a function of dosing temperature

Lead Institution

University of Washington

Principal Investigator

Jason Donev

Project type

Exploratory Research

ASW is a metastable phase of water, which forms when depositing water vapor on a substrate below about 130K. ASW deposited at low temperatures (30-88K) on Au forms three-dimensional clusters at the…

Evaluation of multicomponent proous oxide films

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Xiaohong Li

Project type

Exploratory Research

The objective is to understand processing-microstructure relationships in multicomponent oxide films prepared by evaporative deposition of solution precursors

Evaluation of multicomponent proous oxide films

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Xiaohong Li

Project type

Exploratory Research

The objective is to understand processing-microstructure relationships in multicomponent oxide films prepared by evaporative deposition of solution precursors

Characterization of Aluminosilicate Phases forming under low-silica conditions.

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Shas Mattigod

Project type

Exploratory Research

The objective is to study the formation and transformation of cementitious aluminosilicate phases. SEM with EDX will be used to study the morphology and chemical composition of these solid phases.

Excited states of DNA hairpins

Lead Institution

Northwestern University

Principal Investigator

George Schatz

Project type

Exploratory Research

We propose to investigate theoretically, using time-dependent density functional methods, the excited states of DNA oligomeric structures (hairpins and dumbbells) constituted of 1 to 6 base pairs…

Chrome Valance State Analysis

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Michael Schweiger

Project type

Exploratory Research

Cr+3 and Cr+6 valance state in simulated high-level waste glass samples will be analyzed using XPS in Lab 1216. Minor XRD analysis may be needed using equipment in Lab 1422.

MD Simulation of DNA Oligonucleotides Containing Base Damage (fsd4)

Lead Institution

Washington State University Tri-Cities

Principal Investigator

John Miller

Project type

Exploratory Research

Objectiive:This pilot project will investigate the performance of NWChem for simulating the molecular dynamics of double-strand DNA when one of the base pairs in a dodecamer (approximately one turn…

Proteomic analysis of wild type and soil-colonization deficient strains of Pseudomonas fluorescens

Lead Institution

Tufts University School of Medicine

Principal Investigator

Stuart Levy

Project type

Exploratory Research

Proteomic analysis of wild type and soil-colonization deficient strains of Pseudomonas fluorescens A significant step towards developing effective genetically modified-microbes for bioremediation…

Strengthening mechanisms in ultra high strength corrosion resistant steel

Lead Institution

Portland State University

Principal Investigator

William Wood

Project type

Exploratory Research

We are investigating the precipitation reactions that occur during high speed induction heat treatment of a ultra high strength corrosion resistant steel containing C,N,Cr, Ti V, Mo. We would like to…

Supercritical Fluid Immersion Deposition of Metal Films on Semiconductor

Lead Institution

University of California, San Diego

Principal Investigator

Xiang-Rong Ye

Project type

Exploratory Research

Objective: Currently one challenging issue in electronic industry is filling trenches and small features for interconnection. However, conventional CVD process can't accomplish this purpose…

Analysis of Silicon Nitride Thin Films

Lead Institution

Idaho State University

Principal Investigator

Rene Rodriguez

Project type

Exploratory Research

We would like to determine the atomic composition as a function of depth for thin films of silicon nitride deposited on silicon wafers. We are also interested in the cyrstallinity of the material as…

Community-Based Biosignatures of Exposure and Functional Response in the Sediment-Water Interface of the Hyporheic Zone and Periphyton Community in River Systems

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Amoret Bunn

Project type

Exploratory Research

Biomarkers that indicate change in the biotic community due to the presence of contamination in the sediment-water interface can be used as part of monitoring programs assessing remediation…

Community-Based Biosignatures of Exposure and Functional Response in the Sediment-Water Interface of the Hyporheic Zone and Periphyton Community in River Systems

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Amoret Bunn

Project type

Large-Scale EMSL Research

Biomarkers that indicate change in the biotic community due to the presence of contamination in the sediment-water interface can be used as part of monitoring programs assessing remediation…

Microbial Reduction of Illite and Glauconite

Lead Institution

Miami University

Principal Investigator

Hailiang Dong

Project type

Exploratory Research

This project investigates reduction of Fe(III) in structure of sedimentary illite and glauconite by Shewanella oneidensis CN32, and possible implications for bioremediation and subsurface microbial…