Projects

Integrated Modeling and Experimental Evaluation of Hydrodynamic and Microbial Controls on DNAPL Dissolution and Detoxification

Lead Institution

Michigan Technological University

Principal Investigator

Eric Seagren

Project type

Large-Scale EMSL Research

Tetrachloroethene (PCE) and trichloroethene (TCE) are among the most common organic subsurface contaminants at DOE and many other contaminated sites. In situ bioremediation of aqueous-phase PCE and…

Fundamentals of Carbonate Formation: Interactions of CO2 with Supported Metal Oxide Clusters

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Xiao Lin

Project type

Large-Scale EMSL Research

We propose to study the fundamental aspects of CO2 adsorption and reactions leading to carbonate (CO32-) formation on well-characterized surfaces and supported nanoclusters of model oxides. Well…

Pore Connectivity in Hanford Sediments and Natural Rock

Lead Institution

The University of Texas at Arlington

Principal Investigator

(Max) Qinhong Hu

Project type

Large-Scale EMSL Research

Pore connectivity in natural sediments and rock has important short- and long-term effects on fluid flow and chemical transport. These effects have implications for the remediation of contaminated…

Meta-Proteomic Analysis of Hg and U Contaminated Microbial Communities

Lead Institution

Oak Ridge National Laboratory

Principal Investigator

Dwayne Elias

Project type

Large-Scale EMSL Research

The sulfate- and Fe(III)- reducing bacteria (SRB and IRB) are primarily responsible for the biotransformation of metals and radionuclides in porous subsurface sediments. Desulfovibrio spp. and…

Reconstructing the Mycobacterium Tuberculosis Metabolic Model

Lead Institution

National Institute of Allergy and Infectious Diseases

Principal Investigator

Clifton Barry

Project type

Large-Scale EMSL Research

Tuberculosis (TB) kills 3 million people every year, and the rising tide of drug-resistant TB threatens to overwhelm global health programs. New and improved drugs are urgently needed to shorten the…

Charge Transfer, Transport, and Reactivity in Complex Molecular Environments

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Ram Devanathan

Project type

Large-Scale EMSL Research

Proton transport in polymer electrolyte membranes (PEMs) for fuel cells is of fundamental scientific interest and holds practical importance, because of the efficient conversion of fuel chemical…

Mechanistic Understanding of Glass-Water Reaction

Lead Institution

Oak Ridge National Laboratory

Principal Investigator

Eric Pierce

Project type

Large-Scale EMSL Research

The construction of valid rate models, such as the Transition State Theory Kinetic Rate Equation, to describe the dissolution of rock-forming minerals, the evolution of soils, and the corrosion…

Multiscale Modeling of Radiation Effects in Novel Nuclear Waste Forms

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Ram Devanathan

Project type

Large-Scale EMSL Research

The safe immobilization of high-level nuclear waste is one of the major challenges facing humanity today. This multi-scale computational effort aims to obtain a fundamental understanding of…

Environmental Chemistry of Fe-containingMineral Dust Particles

Lead Institution

Lawrence Berkeley National Laboratory

Principal Investigator

Mary Gilles

Project type

Large-Scale EMSL Research

Iron is a key element for growth and metabolism in marine organisms. Solubilization of iron in mineral dust particles resulting from its atmospheric chemistry may substantially increase its…

Design of plasmonic probe tips to control light on the nanoscale for imaging and spectroscopy with ultrahigh spatial and temporal resolution

Lead Institution

University of Colorado at Boulder

Principal Investigator

Bernd Raschke

Project type

Large-Scale EMSL Research

The optical probing of matter with simultaneous nanometer spatial and femtosecond temporal resolution has remained a great challenge. Here, using focused ion beam milling we will tune the optical…

Reverse Methanogenesis: Validating the Hypothesis with Lineage-Resolved Environmental Proteomics

Lead Institution

University of British Columbia

Principal Investigator

Steven Hallam

Project type

Large-Scale EMSL Research

In marine sediments three known lineages of anaerobic methane oxidizing archaea (ANME-1, 2 and 3) filter up to ~384 Tg of the greenhouse gas methane annually, greatly reducing methane flux from ocean…

Dynamics of Bacterial Phosphoglucomutase via NMR Relaxation

Lead Institution

University of Missouri - Columbia

Principal Investigator

Steven Van Doren

Project type

Large-Scale EMSL Research

A bacterial enzyme known as phosphomannomutase / phosphoglucomutase (PMM/PGM) is required in the biosynthesis of the sugar capsule. Bacteria use this coating of complex carbohydrates in forming their…

Tying Distinct Nanoparticle Properties to Cell Surface Interactions and Intracellular Fate

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Joel Pounds

Project type

Large-Scale EMSL Research

The increasing use of engineered nanomaterials in industrial and medical applications is expected to increase both unintended environmental or occupational exposures and intended medical or direct…

Abiotic Reduction of U(VI) by Sorbed Fe(II) and the Implications for Field-Scale Bioremediation at the Rifle IFRC Project Site

Lead Institution

Lawrence Berkeley National Laboratory

Principal Investigator

Patricia Fox

Project type

Large-Scale EMSL Research

Uranium (U) contamination of aquifers is a problem at a number of DOE sites, and bioremediation is currently being investigated at the Integrated Field Research Challenge Site at Rifle, CO as a…

Interfacial and Multiphase Chemistry of Metal-Containing Atmospheric Dust Particles

Lead Institution

University of Iowa

Principal Investigator

Vicki Grassian

Project type

Large-Scale EMSL Research

This proposal is to use EMSL capabilities to perform laboratory studies to better understand how the properties of metal-containing atmospheric particles change as they undergo atmospheric transport…

Investigation of anaerobic lignocellulose decomposition in Puerto Rico tropical forest soils

Lead Institution

University of Massachusetts Amherst

Principal Investigator

Kristen DeAngelis

Project type

Large-Scale EMSL Research

As one of the primary objectives of the DOE Joint BioEnergy Institute (JBEI), our project aims to identify and characterize unique microorganisms, enzymes and pathways with novel lignocellulolytic…

Transformation Mechanisms and Kinetics of Fe-(oxyhydr)oxide Reduction and their Impact on Uranium Sequestration

Lead Institution

Stanford Linear Accelerator Center

Principal Investigator

Juan Lezama Pacheco

Project type

Large-Scale EMSL Research

Redox cycling of Fe-(oxyhydr)oxides such as ferrihydrite in naturally or artificially reduced sediments has a major impact on the speciation and stability of uranium. Ferrihydrite is a poorly…

Geobiology of Chemical Weathering: Spatially Explicit Characterization of the Inorganic Chemical Composition of Mycorrhizospheric Biofilms

Lead Institution

Washington State University

Principal Investigator

Chester Keller

Project type

Large-Scale EMSL Research

Rich literatures and recent advances across several fields have set the stage for process-based research into the biogeochemical agency of vascular plants -- in particular, how their physiologies…

The Quaternary Structures of Enamel Proteins at Interfaces Studied by Helium-ion Microscopy (HIM)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Barbara Tarasevich

Project type

Large-Scale EMSL Research

The interactions of proteins at surfaces are of great importance to biomineralizaton processes and to the development and function of biomaterials. Amelogenin is a unique biomineralization protein…

Cell Injury Involving Transmetallation of Gadolinium Based MRI Contrast Agents

Lead Institution

Oregon Health & Science University

Principal Investigator

Wassana Yantasee

Project type

Large-Scale EMSL Research

This EMSL user proposal is directly responsive to Biological Interactions and Dynamics Science Theme. The work involves the fundamental studies on the heterogeneity in cell composition and response…