Projects

The role of protein - mineral interactions for protein cycling in soil and protein extraction efficiency from soils

Lead Institution

Oregon State University

Principal Investigator

Markus Kleber

Project type

Exploratory Research

We intend (1) to improve the ability to detect proteins in physical soil fractions, and (2) to discover preferences of exoenzymes for relevant classes of mineral components in soil. The latter will…

Using Oxygen Isotope Fractionation (delta-18O) in Otoliths to Characterize the Temperature History of Fall Chinook Salmon

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Timothy Linley

Project type

Exploratory Research

Fall Chinook salmon in the Snake River are listed as threatened under the Endangered Species Act. A potential factor limiting their recovery is the impact from hydropower generation on river…

Ab Initio Calculations of Charge Carrier Properties and Excited-State Processes in Scintillator Materials: Advanced Materials and Scintillation Mechanisms

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Renee Van Ginhoven

Project type

Exploratory Research

The development of new and improved materials for radiation detection is driven by unmet detector requirements for nuclear non-proliferation, homeland security, imaging for medical diagnosis and…

Fundamental Studies of Water Splitting on Model TiO2, RuO2 and Mixed TiO2-RuO2 Catalysts

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Michael Henderson

Project type

Large-Scale EMSL Research

The objective of this project is to provide fundamental insights into the roles of co-catalysts in heterogeneous photocatalytic water splitting over model TiO2 and related semiconducting oxide…

Computational Catalyst Design: Controlling Chemical Transformations to Minimize Environmental Impact

Lead Institution

University of Alabama

Principal Investigator

David Dixon

Project type

Large-Scale EMSL Research

There is a critical need to develop new, renewable sources of energy as well as chemical feedstocks. Biomass is a carbon neutral source of energy and can also address issues related to the…

Nanocomposite magnets for energy applications: exploring hard phase/soft phase interfacial properties

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jun Cui

Project type

Exploratory Research

Exchange-spring magnets are nanocomposites that are composed of magnetically hard and soft phases that interact by magnetic exchange coupling. By theory, a composite magnet with ideal nanostructure,…

Surface-supported sub-nano clusters as catalysts

Lead Institution

University of California, Los Angeles

Principal Investigator

Anastassia Alexandrova

Project type

Exploratory Research

The ultimate objective of the proposed research is fundamental understanding and design of novel catalytic interfaces based on ultra-small, sub-nano surface-deposited clusters, with a particular…

Interactions between Functionalized Graphene and Electrochemically Active Materials in Advanced Energy Storage System

Lead Institution

University of Arkansas, Fayetteville

Principal Investigator

Jie Xiao

Project type

Large-Scale EMSL Research

The overall goal of this project is to understand the roles of functionalized graphene in energy storage systems spanning from Li-ion, Li-S to Li-air batteries. Specifically, the morphology of…

Towards a complete structure of the intact bacterial cytokinesis machine

Lead Institution

University of Texas Health Science Center at Houston

Principal Investigator

William Margolin

Project type

Large-Scale EMSL Research

All bacteria need to grow and divide in order to proliferate in the environment. This involves duplication of their genetic material, partitioning the copies to daughter cells, and finally…

Electronic and Optical Properties of Doped Complex Oxide Epitaxial Films and Interfaces

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Scott Chambers

Project type

Large-Scale EMSL Research

The effect of A-cation site and anion-site doping, as well as heteroepitaxial interface formation, on the electronic and optical properties of La-based perovskites will be investigated. Specimens…

Experimental Capabilities and Fundamental Science for Geologic Carbon Sequestration: The PNNL In Situ Supercritical Suite (IS3)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

John Loring

Project type

Large-Scale EMSL Research

This Science Theme proposal requests EMSL access for investigators in the In Situ Supercritical Suite (IS3) component of PNNL's Carbon Sequestration Initiative (CSI). The CSI is a multi-million…

Coupled Surface and Solid-State Charge and Ion Transport Dynamics at Mineral/Water Interfaces: Redox Transformation of the Iron Oxides

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kevin Rosso

Project type

Large-Scale EMSL Research

This EMSL user proposal requests a continuation of EMSL access for a BES Geosciences supported project led by Dr. Rosso at PNNL. The past three years of research under this BES project we have been…

Determining the Conformational Changes within an Active Enzyme-Substrate System on both Sides of the Reaction.

Lead Institution

University of Colorado at Denver

Principal Investigator

Elan Eisenmesser

Project type

Large-Scale EMSL Research

Our objective is to develop solution-based strategies that directly monitor the physical conformational changes that occur within enzymes, both free and during enzyme catalysis. These strategies are…

Genome-enabled studies of key light-dependent metabolic and regulatory switches governing reductant and carbon partitioning in cyanobacteria

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Alex Beliaev

Project type

Large-Scale EMSL Research

The main goal of this proposal is develop and apply an integrated omics approach for systems-level analysis of photosynthetic metabolism in cyanobacteria that will lead to the identification of key…

Computational Chemical Dynamics of Complex Systems

Lead Institution

University of Minnesota

Principal Investigator

Donald Truhlar

Project type

Large-Scale EMSL Research

The ultimate goal of this project is to develop and apply innovative user-friendly high-performance computing techniques and simulation methods for computational chemical dynamics of complex systems…

Computational Study of Colicin Dynamics in Lipid Bilayers

Lead Institution

Bowling Green State University

Principal Investigator

H. Peter Lu

Project type

Exploratory Research

We plan to study the colicin ion channel open-close dynamics involving in protein domains diffuse across the biological membrane under an external electric field. Our work will serve as an adequate…

Understanding structure-function relationships for developing catalysts for energy storage and production reactions.

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Wendy Shaw

Project type

Large-Scale EMSL Research

The DOE Basic Energy Sciences Energy Frontier Research Center entitled “Center for Molecular Electrocatalysis” (Bullock), the DOE Basic Energy Sciences “Modular Energy-Based Approach to Molecular…

Lipid Activity Probes for the Chemical Proteomic Characterization of Protein Targets

Lead Institution

University of Tennessee

Principal Investigator

Michael Best

Project type

Large-Scale EMSL Research

Lipids including diacyglycerol, phosphatidic acid and the phosphatidylinositol polyphosphates regulate numerous critical biological processes, many of which are aberrant in disease or involved in the…

Interfacial Phenomena in Nanostructured Materials under Irradiation

Lead Institution

University of Tennessee

Principal Investigator

William Weber

Project type

Large-Scale EMSL Research

Nanostructured materials provide the opportunity for tailoring physical, electronic, optical, and biological properties for a variety of technological applications, including novel catalysis, sensors…

Rational Design of Ceramic Interfaces for Environmental Technologies

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Ram Devanathan

Project type

Large-Scale EMSL Research

The aim of this research proposal is to advance the fundamental science needed to safely immobilize nuclear waste in durable ceramic matrices. Crystalline ceramics, including polyphase materials,…