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Instruments & Resources

The Environmental Molecular Sciences Laboratory (EMSL) is home to the user facility’s 150 instruments that can be leveraged for biological, environmental, and computing research needs. The instruments and resources are available to researchers who are awarded funding through EMSL’s open call for proposals. The categories below reflect instrument groups for specific research areas. When selected, the instrument group is filtered by the instruments that fall under that category. By reviewing the instrument pages, researchers can learn how the instrumentation can be applied to research. The instrument and resource pages can also be used to identify the instrument owners and Integrated Research Platform area leads to follow up with questions before submitting an abstract to a call for proposal.

Nanospray Desorption Electrospray Ionization Mass Spectrometry

The Nanospray Desorption Electrospray Ionization Mass Spectrometer (nanoDESI) is used for a variety of environmental research projects that are relevant to atmospheric aerosol chemistry, aquatic and soil chemistry, and mass spectrometry imaging of biological samples. This resource is available to researchers worldwide through the EMSL User Program.
Related Instrument Groups
Aerosol Characterization
Omics & Organic Matter Analysis

Lipidomics

The Environmental Molecular Sciences Laboratory (EMSL) offers liquid chromatography tandem mass spectrometry (LC-MS) for lipidomics research, which is available through the EMSL User Program.
Related Instrument Groups
Omics & Organic Matter Analysis

Mass Spectrometry Imaging

The Environmental Molecular Sciences Laboratory's mass spectrometry capabilities allow researchers to investigate the spatial distribution of molecules within biological samples. Mass spectrometry imaging resources are available to researchers who submit proposals and are awarded funding through the EMSL User Program.
Related Instrument Groups
Chemical Imaging
Omics & Organic Matter Analysis

Pyrolysis Gas Chromatography-Mass Spectrometry

The Environmental Molecular Sciences Laboratory offers pyrolysis–gas chromatography–mass spectrometry for method of chemical analysis of environmental applications, including the identification and characterization of micro- and nano-plastic contamination.
Related Instrument Groups
Omics & Organic Matter Analysis

Real Time Mass Spectrometry

The Environmental Molecular Sciences Laboratory (EMSL)'s real time mass spectrometry resources are available to researchers around the world through the EMSL User Program for understanding gas exchanges in diverse biological and environmental systems
Related Instrument Groups
Omics & Organic Matter Analysis

Intermediate Scale Flow Cells

EMSL builds custom flow cells for pore and intermediate scale experiments to study multiphase flow and transport phenomena in saturated and undersaturated subsurface conditions. For pore scale…
Related Instrument Groups
Flow & Transport

Liquid State NMR for Metabolomics

The Environmental Molecular Sciences Laboratory (EMSL) offers liquid state nuclear magnetic resonance capabilities for metabolomics research through the EMSL User Program.
Related Instrument Groups
NMR & EPR
Omics & Organic Matter Analysis

Nanodroplet Processing in One Pot for Trace Samples (NanoPOTS)

The Environmental Molecular Sciences Laboratory offers a microfluidic sample preparation platform called Nanodroplet Processing in One Pot for Trace Samples, or nanoPOTS, for proteomics profiling of biological samples.
Related Instrument Groups
Laboratory Preparations and Cell Separations
Omics & Organic Matter Analysis

Bottom-Up (Fragmented) Proteomics

The Environmental Molecular Sciences Laboratory has a variety of proteomics resources available to the scientific community through open calls for proposals.
Related Instrument Groups
Omics & Organic Matter Analysis

Top-down (Intact) Proteomics

The Environmental Molecular Sciences Laboratory's top-down proteomics resources enable researchers to measure stoichiometry of protein-protein, protein-nucleic acid, protein-ligand, and protein-metal complexes. Resources are also available for precisely defining “proteoforms” at the intact protein level. These capabilities are accessible through open calls for proposals.
Related Instrument Groups
Omics & Organic Matter Analysis

Mass Spectrometry for Organic Matter Analysis

The Environmental Molecular Sciences Laboratory offers Fourier transform ion cyclotron resonance (FTICR) mass spectrometry resources for analyzing organic matter. This instrumentation is available to researchers through open calls for proposals.
Related Instrument Groups
Omics & Organic Matter Analysis

Mass Spectrometry for Metabolomics

The Environmental Molecular Sciences Laboratory has state-of-the-art and advanced mass spectrometry platforms to perform a full range of metabolomics studies. These resources are available for use at no cost to researchers around the world through EMSL's open calls for proposals.
Related Instrument Groups
Omics & Organic Matter Analysis

Soil Hydraulic Property Measurements

Soil hydraulic properties determine the rate at which water and other fluids move through soils. It also determines their water holding capacity, microbial activity, and biogeochemical processes…
Related Instrument Groups
Flow & Transport