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David Springer

Institution
Pacific Northwest National Laboratory

Projects

Platelet proteome for normal and type-2 diabetics

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
David Springer
Project type
Large-Scale EMSL Research
Abstract Our proposal entitled "Platelet proteome for normal and type-2 diabetics" is funded by NIH through an R21 grant. The research is designed to characterize the proteome from human…

Regulated proteolysis and bystander effects in radiation

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
David Springer
Project type
Exploratory Research
Growing evidence suggests that the number of cells adversely influenced by radiation exposure is greater that those receiving a direct radiation hit. We hypothesize that radiation-induced bystander…

Biomarker development for chronic obstructive pulmonary disease

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
David Springer
Chronic obstructive pulmonary disease(COPD) is a common chronic disease effecting a significant portion of humans, particularly those that smoke. The goal of this work is to develop a reliable…

Visualization of Gamma H2AX Foci

Lead Institution
NASA Ames Research Center
Principal Investigator
Marianne Sowa
Project type
Exploratory Research
Genomically unstable cells have been demonstrated to release a "factor" into the medium which when transferred to stable cells results in 100% cell death. First demonstrated by Nagar and…