Mara Kreishman-Detrick

University of Texas Southwestern Medical Center

Projects

Activation of the Arp2/3 Complex by WASP Family Proteins: Probing Individual Subunits by NMR

Lead Institution

University of Texas Southwestern Medical Center

Principal Investigator

Michael Rosen

Project type

Capability Research

The Rho-family GTPases regulate the actin cytoskeleton through activation of the Wiskott-Aldrich Syndrome protein (WASP) family proteins, and they in turn activate the Actin-related protein (Arp) 2/3…