Projects

Developing efficient fungal biocatalysts for on-site enzyme production and for production of chemical building blocks in biorefineries using metabolomic and secretomic profiling

Lead Institution

Aalborg University

Principal Investigator

Mette Lubeck

Project type

Large-Scale EMSL Research

Development of biocatalysts for sustainable production of bioactive molecules from lignocellulosic plant biomass in biorefineries is a rapid growing research area. One of the most important and…

Preparation of Novel Catalytic Materials Using Soft- and Reactive Landing of Ions

Lead Institution

National Dong Hwa University

Principal Investigator

Wen-Ping Peng

Project type

Large-Scale EMSL Research

The proposed work is focused on obtaining a molecular-level understanding of the structure-reactivity relationships of catalytically active small metal clusters and organometallic molecules deposited…

Visualizing the Effects of Engineered Chimeric Growth Factors on Receptor Distribution

Lead Institution

Massachusetts Institute of Technology

Principal Investigator

Linda Griffith

Project type

Large-Scale EMSL Research

Members of the epidermal growth factor receptor (EGFR/HER/ErbB) family - EGFR, HER2, HER3, and HER4 - regulate diverse cell behaviors including survival, proliferation, differentiation and migration…

Large-scale computational modeling of the chemical transformation of actinide elements at interfaces

Lead Institution

Lawrence Berkeley National Laboratory

Principal Investigator

Wibe De Jong

Project type

Large-Scale EMSL Research

Subsurface migration of radioactive waste resulting from nuclear energy and weapons production is a critical issue to the U.S. Department of Energy (DOE), and the safe and cost-effective disposal of…

Cluster Model Studies of Condensed Phase Phenomena at Well-Defined Conditions

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Xuebin Wang

Project type

Large-Scale EMSL Research

This program is aimed at obtaining a microscopic understanding of solution chemistry and condensed phase phenomena using gas phase clusters as model systems.Our current focus is on the microsolvation…

Mass Spectrometry Imaging of Microbial Communities

Lead Institution

University of California, San Diego

Principal Investigator

Pieter Dorrestein

Project type

Large-Scale EMSL Research

Despite our significant technological advancements, the solutions to many of humanities lingering problems such as bioremediation of toxic heavy metal environmental contaminants, creation of…

Biogeochemical transformation of soil Fe- and Mn- mineral phases along a redox gradient: Implications for C sequestration

Lead Institution

University of Delaware

Principal Investigator

Donald Sparks

Project type

Large-Scale EMSL Research

Iron (Fe) and manganese (Mn) oxides, hydroxides and oxyhydroxides are well known redox-sensitive mineral components of environmental systems. Iron minerals in soils and sediments occur in a variety…

Reactivity of iron-bearing phyllosilicates with uranium and chromium through redox transitions zones

Lead Institution

Miami University

Principal Investigator

Hailiang Dong

Project type

Large-Scale EMSL Research

Iron-bearing phyllosilicate minerals are widely distributed and often account for about half of the iron in soils and sediments. They play an important role in environmental processes such as…

Enamel biomineralization: Solution- and solid-state NMR studies of a natural protein-mineral interfaces

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Garry Buchko

Project type

Large-Scale EMSL Research

Dental enamel, the 1-2 mm layer of elongated carbonated hydroxayapatite on the outer layer of the tooth, is the hardest tissue in the human body. It needs to be strong because it is exposed to…

Horizontal Gene Transfer in Porous Media: A Real Time Microscopic Investigation

Lead Institution

University of Illinois at Urbana-Champaign

Principal Investigator

Thanh Nguyen

Project type

Large-Scale EMSL Research

Horizontal gene transfer is widespread among bacteria and is an important component of microbial evolution and trait dispersal. Specifically, gene transfer can create new metabolic capabilities, e.g…

Excitation and Desorption of Nano-crystalline ZrO2

Lead Institution

University College London

Principal Investigator

Alexander Shlyuger

Project type

Large-Scale EMSL Research

This project is focused on integrated theoretical and experimental studies of the interaction of light with nanoscale oxide materials of fundamental interest to the fields of photo-catalysis,…

Characterization of the affects of specialized acyl carrier proteins on unusual LPS-hydroxy fatty acids in Geobacter metallireducens

Lead Institution

Miami University

Principal Investigator

Theresa Ramelot

Project type

Large-Scale EMSL Research

Many bacteria have specialized acyl carrier proteins (ACPs) that are involved in synthesis of diverse lipopolysaccharides (LPS). Diversity within LPS aids in survival of Gram-negative bacteria in…

Atomic and electronic structures of interfaces of complex oxides

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Petr Sushko

Project type

Large-Scale EMSL Research

Oxide interfaces, superlattices and solid solutions provide opportunities for generating materials with novel properties, providing the atomic structures of the interface and near interface regions…

Developing More Efficient Fuel Cells Using Computational Methods

Lead Institution

Los Alamos National Laboratory

Principal Investigator

Neil Henson

Project type

Large-Scale EMSL Research

This project proposes to use a number of state-of-the-art, highly parallelised computational chemistry tools in order to rationalise the fundamental chemical processes occurring at the atomic level…

Epitaxial thin films as model battery electrodes - The reaction front and ionic diffusion

Lead Institution

University of Colorado at Boulder

Principal Investigator

Michael Toney

Project type

Large-Scale EMSL Research

Energy conversion and storage is of great importance to a sustainable environment and meeting our energy needs. However, fundamental scientific understanding of rechargeable batteries is far behind…

The Lignin Enigma: Turning the Corner

Lead Institution

Washington State University

Principal Investigator

Norman Lewis

Project type

Large-Scale EMSL Research

Lignins (Nature's second most abundant terrestrial plant substances) provide structural support for plants to stand upright, to conduct water/nutrients, and as barriers to opportunistic…

Connecting genomic capabilities to physiology, photosynthesis and carbon cycling

Lead Institution

Monterey Bay Aquarium Research Institute

Principal Investigator

Alexandra Worden

Project type

Large-Scale EMSL Research

More than 50% of global primary production is performed by land plants and green algae. Of all algae green algae are the most closely related to land plants and therefore provide powerful single cell…

The Organic Surfactant Pool on Secondary Organic Aerosol Particles

Lead Institution

Northwestern University

Principal Investigator

Franz Geiger

Project type

Large-Scale EMSL Research

Secondary organic aerosol (SOA) particles particles rank among the least understood atmospheric constituents in the climate system. Key questions concern their poorly quantified roles in cloud…

A Molecular-to-Regional Scale Understanding of Secondary Organic Aerosol Formation

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jerome Fast

Project type

Large-Scale EMSL Research

Our hypothesis is that a better understanding of fast-reacting processes is needed to make a breakthrough in parameterizing secondary organic aerosols (SOA) for the next generation climate models. To…

Ice Nucleation Propensity of Biological Particles

Lead Institution

Xiamen University

Principal Investigator

Bingbing Wang

Project type

Large-Scale EMSL Research

The proposed study will investigate the ice nucleation propensity of atmospheric biological particles using a novel experimental platform developed in EMSL by our group. We will determine…