Projects

Development of a Microfluidics Flow and Transport Laboratory

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Mart Oostrom

Project type

Large-Scale EMSL Research

The Environmental Spectroscopy and Biogeochemistry (ESB) Facility, in collaboration with the University of Illinois at Champaign/Urbana, proposes to develop a microfluidics capability to investigate…

13C NMR Investigation of Occluded Carbonate in Aluminum (Oxy)Hydroxides.

Lead Institution

Umea University

Principal Investigator

Jean-Francois Boily

Project type

Large-Scale EMSL Research

We outline a plan to monitor the occlusion of carbonate in minerals under well-controlled systems. This study builds upon ongoing work currently funded by the Office of Basic Energy Science,…

chlorinated methane hydrolysis rates

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James Amonette

Project type

Large-Scale EMSL Research

The purpose of the work proposed here is to develop accurate physical chemical data for the hydrolysis rates of carbon tetrachloride (CT) and chloroform (CF) under conditions (temperature, pH,…

Chlorinated Methane Hydrolysis Rates

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James Amonette

Project type

Large-Scale EMSL Research

The purpose of the work proposed here is to develop accurate physical chemical data for the hydrolysis rates of carbon tetrachloride (CT) and chloroform (CF) under conditions (temperature, pH,…

Characterization of amorphous oxide transparent semiconductors

Lead Institution

Oregon State University

Principal Investigator

Gregory Herman

Project type

Large-Scale EMSL Research

Recently the field of transparent optoelectronic devices has seen tremendous advances due in part to new inorganic materials developments, processing capabilities, and novel applications. …

Experimental Validation of Multiscale Modeling Approach to Materials Discovery for Radiation Detection Materials

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Charles Henager

Project type

Large-Scale EMSL Research

In the field of crystal growth modeling, it is not currently possible to specify the atomistic accuracy at the continuum scale in a rigorous manner [1]. Continuum scale models of growth are robust,…

Magnetic Resonance Microscopy of Ozone-Induced Lung Injury

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kevin Minard

Project type

Large-Scale EMSL Research

The goal for this project is to develop a three-dimensional (3D), geometric database that describes the remodeling of respiratory airways in Rhesus monkeys following ozone challenge.

Correlating the active site structure of copper metalloproteins with their spectroscopic and chemical properties

Lead Institution

University of Nebraska - Lincoln

Principal Investigator

Gerard Harbison

Project type

Large-Scale EMSL Research

We propose to implement 63Cu and 65Cu, in combination with quantum chemical calculations, to study the metal sites of blue copper proteins, oxidase enzymes, and copper chaperones. Living systems &…

Interactions Between Domains in Dematin, a Key Component of the Red Blood Cell Junctional Complex.

Lead Institution

Boston University School of Medicine

Principal Investigator

Christopher Mcknight

Project type

Large-Scale EMSL Research

The regulation and maintenance of the actin cytoskeleton is essential for all eukaryotic cells. The "villin-type headpiece" family of actin-associated proteins contains a modular C…

Tuning the chemistry and configuration of oxide nanostructures for energy and environmental applications

Lead Institution

University of Central Florida

Principal Investigator

Sudipta Seal

Project type

Large-Scale EMSL Research

Materials development based on a fundamental understanding of their behavior has gained a new impetus with the advent of nanotechnology. Oxide nanostructures are among the most widely studied…

Neuropeptides and vasoactive protein detection from human skin.

Lead Institution

University of Oregon

Principal Investigator

Christopher Minson

Project type

Large-Scale EMSL Research

I am submitting this proposal through the EMSL Science Theme Call: Biological Interactions and Dynamics. The overarching goal of this proposal is to develop novel approaches to recover and identify…

Morphology of colloids formed in soils reacted with simulated Hanford Waste Tank solutions and the distribution of incorporated and adsorbed cesium in the colloids

Lead Institution

Washington State University

Principal Investigator

Youjun Deng

Project type

Exploratory Research

High-level radioactive waste solutions stored in the underground tanks at Hanford sites have leaked into the vadose zone. The waste tank supernatants are known to consist of solutions with high pH (9…

Integrated NMR/SIP technologies for the functional and structural characterization of microbial communities

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Johannes Scholten

Project type

Large-Scale EMSL Research

We propose to combine stable isotope probing (SIP) of DNA (SIP-DNA) with real-time on-line SIP-nuclear magnetic resonance (SIP-NMR) analysis of microbial community metabolism. SIP-NMR provides access…

Imaging Respiratory Structure and Function In Laboratory Animals

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kevin Minard

Project type

Large-Scale EMSL Research

The goal for this NIH-funded project is to develop Magnetic Resonance (MR) imaging for visualizing - 1) airway architecture, 2) lung mechanics, 3) gas flow, and 4) particulate deposition in live…

Microscale and spectroscopic investigations in geochemical and microbiological systems

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

John Zachara

Project type

Large-Scale EMSL Research

Apply experimental manipulation and field investigations to understanding the behavior of selected chemical and microbial components in natural systems. The research is targeted towards compounds…

MRI of chronic obstructive pulmonary disease

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kevin Minard

Project type

Large-Scale EMSL Research

Proposed work will be performed using normal rats and emphysematous counterparts. The specific aims are to - 1) quantify regional alveolar airway destruction in vivo using 19F gas MRI techniques…

COMBINED NMR/OPTICAL MICROSCOPY OF BIOFILM PHYSIOLOGY STUDIES

Lead Institution

Washington State University

Principal Investigator

Paul Majors

Project type

Large-Scale EMSL Research

Bacterial biofilms are found nearly everywhere in nature. Microbial metabolism and phenotype vary rapidly within a biofilm - this is at least partly responsible for their metabolic diversity and…

Fundamental understanding of charge transfer from a Ru-based dye adsorbate to a TiO2(110) surface

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Michael Henderson

Project type

Large-Scale EMSL Research

Ru-based dye-sensitized TiO2 solar cells have attracted significant attention because of their potential use in photovoltaic cells[1,2]. These devices utilize films of optically transparent TiO2…

Bradley Tebo's Proposal

Lead Institution

University of Washington

Principal Investigator

Bradley Tebo

Project type

Large-Scale EMSL Research

Mn oxides are important mineral phases in a variety of environments and have potential application in solar energy capture and conversion and contaminant remediation technologies. In nature,…

Integrated Experimental and Modeling Studies on Aerosol Evolution and Aging

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Rahul Zaveri

Project type

Large-Scale EMSL Research

The objectives of this project are to characterize the time evolution of aerosol size, density, composition, and mixing state in an aerosol chamber, and b) link experiments to the development and…