Skip to main content

Erhu Cao

Institution
University of Utah
ORCID
ORCID logo 0000-0003-3102-5692

Projects

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
James Evans
PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

Structures and Mechanisms of the Cation Chloride Cotransporters

Lead Institution
University of Utah
Principal Investigator
Erhu Cao
The secondary active cation-chloride cotransporters (CCCs) utilize the Na+ and/or K+ gradients created by the Na+-K+-ATPase to move Cl- into or out of cells. The CCCs consist of three Na+-dependent…

Structural mechanisms of the polycystic kidney disease proteins

Lead Institution
University of Utah
Principal Investigator
Erhu Cao
Polycystin-1 and polycystin-2 (also known as PKD1 and PKD2) are fundamental for normal development and functioning of the renal and cardiovascular systems. Mutations in either PKD1 or PKD2 genes…

Structural basis of regulation of PKD2 by steroids

Lead Institution
University of Utah
Principal Investigator
Erhu Cao
Polycystic kidney disease 1 (PKD1) and PKD2 are fundamental for normal development and functioning of the renal and cardiovascular systems and, when rendered defective by genetic mutations, cause a…

Structural Mechanisms of Renal Sensory and Transport Proteins

Lead Institution
University of Utah
Principal Investigator
Erhu Cao
The kidneys regulate blood composition, pressure, and volume, balance electrolytes and acid-base, and reabsorb most salts and nutrients from the initial renal filtrate while excreting metabolic…