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Jeffrey Mclean

Institution
University of Washington

Projects

COMBINED NMR/OPTICAL MICROSCOPY OF BIOFILM PHYSIOLOGY STUDIES

Lead Institution
Washington State University
Principal Investigator
Paul Majors
Project type
Large-Scale EMSL Research
Bacterial biofilms are found nearly everywhere in nature. Microbial metabolism and phenotype vary rapidly within a biofilm - this is at least partly responsible for their metabolic diversity and…

NMR/OPTICAL Microscopy Studies of Oral Plaque Ecology

Lead Institution
University of California, Los Angeles
Principal Investigator
Wenyuan Shi
Project type
Large-Scale EMSL Research
Current tooth decay (dental caries) prevention methods include enamel hardening with fluoride and bacterial removal via mechanical and general antimicrobial approaches. These methods are based on the…

In situ monitoring of arginine in living dental biofilms

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Ryan Renslow
Dental caries disease is one of the most widespread diseases globally. A hallmark of supragingival microbial communities is the ability to rapidly metabolize carbohydrates, which dramatically reduces…

Combined NMR/Optical Microscopy for Oral Biofilm Physiology Studies

Lead Institution
Washington State University
Principal Investigator
Paul Majors
Project type
Capability Research
Dental caries disease is one of the most prevalent and costly bacterial infections in humans. Caries and associated tooth decay are strongly correlated with a pH decrease induced by oral biofilms …