Stephen Lindemann

Untangling the Complexity of Microbial Networks by Using Simplified Natural Communities

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

H Wiley

The overall goal of this proposal is to understand the dynamics of both microbial populations and their gene regulatory networks in response to environmental perturbations and to elucidate mechanisms…

Untangling the complexity of phototroph-heterotroph interactions in the lab and in the field

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

H Wiley

Project type

Large-Scale EMSL Research

Despite the fact that ubiquitous microbial interspecies interactions form the foundation of energy flow as well as the biogeochemical cycling of carbon and other elements within natural environments,…

FECB: A Functional Encyclopedia of Cyanobacteria - Building the knowledge framework for an enhanced understanding of carbon and nitrogen cycling

Lead Institution

University of California, Davis

Principal Investigator

Matthias Hess

Project type

FICUS Research

There has been a great interest by the Department of Energy (DOE) to increase the phylogenetic coverage of genome sequences from across the phyla archaea and bacteria – including cyanobacteria. The…

Quantifying the functional and structural states of dynamic microbial communities

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James Fredrickson

Project type

Large-Scale EMSL Research

The overall goal of this proposal is to provide a quantitative framework in which to compare species-resolved patterns of gene expression, allowing comparison of the effects of perturbations of…

Biosystems Analysis for Determining the Impact of Nutrient Uptake on Autotroph-Heterotroph Interactions within Cyanobacterial Consortia

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Stephen Callister

Project type

Large-Scale EMSL Research

The exchange of carbon and other nutrients between microorganisms is a key factor in the establishment of microbial interactions and trophic levels. Depending upon the nutrient, the establishment of…

Spatially-resolved, consortial approaches towards a mechanistic understanding of soil nitrogen fate

Lead Institution

Purdue University

Principal Investigator

Stephen Lindemann

Nitrogen acquisition is a key determinant of plant productivity and the fate of nitrogen, both applied and endogenous, is largely controlled by microbial processes. Furthermore, microbially-induced…

COVID-19: Elucidating the role of the microbiome in COVID-19 induced hyperinflammation

Lead Institution

Purdue University

Principal Investigator

Stephen Lindemann

Project type

Limited Scope

Efforts to manage the global pandemic caused by SARS-CoV-2 have been hampered by our poor understanding of critical factors that determine the short-term and long-term health effects of COVID-19…

Projects

Untangling the Complexity of Microbial Networks by Using Simplified Natural Communities

Untangling the complexity of phototroph-heterotroph interactions in the lab and in the field

FECB: A Functional Encyclopedia of Cyanobacteria - Building the knowledge framework for an enhanced understanding of carbon and nitrogen cycling

Quantifying the functional and structural states of dynamic microbial communities

Biosystems Analysis for Determining the Impact of Nutrient Uptake on Autotroph-Heterotroph Interactions within Cyanobacterial Consortia

Spatially-resolved, consortial approaches towards a mechanistic understanding of soil nitrogen fate

COVID-19: Elucidating the role of the microbiome in COVID-19 induced hyperinflammation