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Projects

As a scientific user facility, the Environmental Molecular Sciences Laboratory (EMSL) provides expertise, instrumentation, and resources to 250 projects each year. 

Projects displayed below reflect information and abstracts that were published before April 30, 2024. To review current EMSL user projects, visit Science Central™.

  • Projects beginning at or after given date.
    Projects ending at or before given date.

Computer Simulation of Optical Spectroscopy

Lead Institution
Bowling Green State University
Principal Investigator
H. Peter Lu
Project type
Exploratory Research
Using theoretical model and numerical simulation software to calculate the Raman spectral frequency and chemical bonding identification, as well as related molecular structures.

Unraveling the Molecular Biology of Host-Pathogen Interactions

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Liang Shi
Project type
Exploratory Research
Macrophages play an important role in the pathogenesis of Salmonella infection. Critical to the ability of macrophages to kill the Salmonella is the activity of the divalent metal ion transporter…

Peptide Observation Model

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Lars Kangas
Project type
Exploratory Research
Washington State University (WSU) student Luning Wang will model the probability of peptides being identified in spectrometry as a part of PNNL's effort in increasing identification confidence…

Photoreflectivity in Ge/Si thin films

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Kenneth Beck
Project type
Exploratory Research
We are measuring the photoreflectivity at 750-800 nm in specially prepared Ge thin films deposited on Si/SiN substrates. The measurements will allow us to estimate the actual free carrier lifetime…

Functional pathway tracing

Lead Institution
Molecular Research Institute
Principal Investigator
Roger Brent
Project type
Exploratory Research

Identification of protein components of vaccinia virus particles

Lead Institution
National Institutes of Health
Principal Investigator
Bernard Moss
Project type
Exploratory Research
Vaccinia virus, the prototype member of the poxvirus family, is predicted to encode nearly 200 proteins. The infectious particle has a complex structure consisting of a lipoprotein membrane…

Surface Characterization of Ambient Ultrafine Particles

Lead Institution
Central Washington University
Principal Investigator
Eric Bullock
Project type
Exploratory Research
The ultrafine fraction (<0.1 mm diameter) of ambient particulate matter (PM) caused by combustion has recently been shown to induce significant oxidative stress in macrophages and epithelial cells…

Routine SEM analysis of lysed Bacillus spores

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Cindy Bruckner-Lea
Project type
Exploratory Research
The research included in this proposal involves the routine SEM analysis of Bacillus thuringiensis and Bacillus atrophaeus spores. SEM analysis will allow us to determine the extent of physical…